3',5'-Di-O-acetyl O6-Benzyl-2'-deoxyguanosine CAS 144640-75-5
| CAS No. | 144640-75-5 |
| Molecular Formula | C21H23N5O6 |
| Molecular Weight | 441.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3',5'-Di-O-acetyl O6-Benzyl-2'-deoxyguanosine (C21H23N5O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3',5'-Di-O-acetyl O6-Benzyl-2'-deoxyguanosine (CAS 144640-75-5) is a high-purity analytical reference standard with the molecular formula C21H23N5O6 and a molecular weight of 441.44 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H23N5O6 |
| Molecular Weight | 441.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 5 |
Recommended Standards
- Pitavastatin Impurity 51 (CAS 1187966-93-3)
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- N-Fmoc-Aminocoumarin-4-acetic acid (CAS 378247-75-7)
- Pemetrexed Impurity (CAS 1644286-35-0)
- 6-Amino-3-(3,4-dimethoxyphenethyl)-2H-benzo[e][1,3]oxazine-2,4(3H)-dione (CAS 900015-13-6)
- 8-[6-(Quinolin-8-yl)pyridin-2-yl]quinoline (CAS 914090-70-3)
- Aloperine (CAS 56293-29-9)
- 5,10-Bis(4-(1-phenyl-1H-benzo[d]imidazol-2-yl)phenyl)-5,10-dihydrophenazine (CAS 1638702-85-8)
- N-[2-(2-Methoxyphenyl)ethyl]-N-methylamine (CAS 104338-26-3)
- N-(3-chloro-4-methylphenyl)-2-(2-ethoxy-4-formyl-6-iodophenoxy)acetamide (CAS 553630-07-2)
- Methyl 2-aminopent-4-ynoate (CAS 70837-20-6)
- 5-(Methylsulfonyl)pyridin-2-amine (CAS 35196-11-3)
- 2-Amino-1-(1H-indol-3-yl)ethanone hydrochloride (CAS 53552-11-7)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
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