Rocuronium Bromide EP Impurity E CAS 1190105-65-7
| CAS No. | 1190105-65-7 |
| Molecular Formula | C32H53N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 593.69 g/mol gives Rocuronium Bromide EP Impurity E distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Rocuronium Bromide EP Impurity E (CAS 1190105-65-7), a pharmacopoeial impurity reference standard (molecular formula C32H53N2O3Br, MW 593.69 g/mol) used for the identification and quantification of trace impurities in APIs.
Rocuronium Bromide EP Impurity E (C32H53N2O3Br) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rocuronium Bromide EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C32H53N2O3 Br |
| Molecular Weight | 593.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Rocuronium Standards
- Rocuronium Impurity 51 (CAS 103088-58-0)
- Rocuronium Impurity 15 (CAS 10429-07-9)
- Rocuronium Bromide Impurity 20 (CAS 1145787-10-5)
- Rocuronium Impurity 14 (CAS 1190105-60-2)
- Rocuronium Bromide EP Impurity D (CAS 1190105-63-5)
- Rocuronium Bromide EP Impurity F (CAS 1190105-66-8)
- Rocuronium Bromide EP Impurity H (CAS 1190105-67-9)
- Rocuronium Bromide Impurity 24 (CAS 119302-19-1)
Recommended Standards
- Trazodone impurity 77 (CAS 1799917-53-5)
- Cholecalciferol Impurity 28 (CAS CATO-C4X-158628)
- Cefazolin EP Impurity D(Cefazolin USP RC J) (CAS 32510-61-5)
- 1-[2-(6-Chloro-pyrazin-2-yl)-piperidin-1-yl]-ethanone (CAS 1316225-06-5)
- 8-Fluoro-2-methyl-4H-benzo[d][1,3]oxazin-4-one (CAS 1044749-59-8)
- 2-Amino-2-(4-isopropylphenyl)acetic acid (CAS 126746-20-1)
- 3-(Dimethylamino)propyl acrylate (CAS 18526-07-3)
- 1185301-61-4 4-(4-Methyl-4H-[1,2,4]triazol-3-yl)-piperidinedihydrochloride (CAS 1185301-61-4)
- 2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carbonitrile (CAS 60467-72-3)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com