Rocuronium Bromide EP Impurity H CAS 1190105-67-9
| CAS No. | 1190105-67-9 |
| Molecular Formula | C32H49N2O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Rocuronium Bromide EP Impurity H (CAS 1190105-67-9), a pharmacopoeial impurity reference standard (molecular formula C32H49N2O4Br, MW 605.66 g/mol) used for the identification and quantification of trace impurities in APIs.
Rocuronium Bromide EP Impurity H (C32H49N2O4Br) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C32H49N2O4 Br |
| Molecular Weight | 605.66 g/mol |
| Purity | >80% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Rocuronium Standards
- Rocuronium Impurity 51 (CAS 103088-58-0)
- Rocuronium Impurity 15 (CAS 10429-07-9)
- Rocuronium Bromide Impurity 20 (CAS 1145787-10-5)
- Rocuronium Impurity 14 (CAS 1190105-60-2)
- Rocuronium Bromide EP Impurity D (CAS 1190105-63-5)
- Rocuronium Bromide EP Impurity E (CAS 1190105-65-7)
- Rocuronium Bromide EP Impurity F (CAS 1190105-66-8)
- Rocuronium Bromide Impurity 24 (CAS 119302-19-1)
Recommended Standards
- Guaifenesin EP Impurity B (CAS 14007-09-1)
- Treprostinil Impurity 14 (CAS CATO-C4X-211614)
- Dapagliflozin impurity N1 (CAS 960494-15-9)
- N1-(2-Chlorophenyl)benzene-1,2-diamine (CAS 74864-94-1)
- Diethyl 5-Amino-3-methylthiophene-2,4-dicarboxylate (CAS 4815-30-9)
- (2r,3s)-3-(acetyloxy)-1,4-bis(acetylsulfanyl)butan-2-yl acetate 4214-85-1 KST-1A4773 (CAS 4214-85-1)
- Fmoc-(S)-2-Amino-5-morpholinopentanoic acid (CAS 2350138-22-4)
- 2-Butyramidopropanoic acid (CAS 55930-29-5)
- 1-(4-Bromophenyl)-3-methylthiourea (CAS 61449-55-6)
- Des-Gly29,30-Tirzepatide (CAS CATO-CPTD788944)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com