Sofosbuvir Impurity 22 CAS 1190308-01-0
| CAS No. | 1190308-01-0 |
| Molecular Formula | C22H29FN3O9P |
| Molecular Weight | 529.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Sofosbuvir Impurity 22 (CAS 1190308-01-0, C22H29FN3O9P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C22H29FN3O9P, Sofosbuvir Impurity 22 contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 529.45 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sofosbuvir Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H29FN3O9P |
| Molecular Weight | 529.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Sofosbuvir Standards
- Sofosbuvir (CAS 1190307-88-0)
- Sofosbuvir Impurity 23 (CAS CATO-C4X-105223)
- Sofosbuvir Impurity 24 (CAS CATO-C4X-105224)
- Sofosbuvir Impurity 25 (CAS CATO-C4X-105225)
- Sofosbuvir Impurity 26 (CAS CATO-C4X-105226)
- Sofosbuvir Impurity 27 (CAS CATO-C4X-105227)
- Sofosbuvir Impurity 28 (CAS CATO-C4X-105228)
- Sofosbuvir Impurity 29 (CAS CATO-C4X-105229)
Recommended Standards
- (S)-(((2R,3R,4R,5R)-D-Sofosbuvir Isomer (CAS 1496552-28-3)
- D-Alanine Sofosbuvir (CAS 1064684-71-4)
- Fluconazole Impurity 55 (CAS CATO-C4X-101955)
- Fluconazole Impurity 47 (CAS CATO-C4X-101947)
- Phytomenadione/Vitamin K1 Impurity 134 (CAS 76337-16-1)
- Piperazine Impurity 14 (CAS 58226-19-0)
- Glutathione Impurity 19 Ditrifluoroacatate (CAS 70555-25-8 (free base))
- 1-Cyclopropoxy-2,4-diethylbenzene (CAS 1243443-20-0)
- 2-Chloro-1-(2,5-dimethyl-1-phenyl-1h-pyrrol-3-yl)propan-1-one (CAS 742118-86-1)
- Alectinib Impurity 36 (CAS CATO-C4X-283636)
- 634150-90-6 Benzenemethanamine, 4-ethoxy-3-fluoro-alpha-methyl- (9CI) (CAS 634150-90-6)
- Droperidol Impurity 5 (CAS 65053-26-1)
- 3-Amino-2-hydroxy-3-phenylpropanamide hydrochloride (CAS 1956332-39-0)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com