Sofosbuvir Impurity 23 CAS CATO-C4X-105223
| CAS No. | CATO-C4X-105223 |
| Molecular Formula | C22H29FN3O9P |
| Molecular Weight | 529.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sofosbuvir Impurity 23 is closely related to a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Sofosbuvir Impurity 23 (CAS CATO-C4X-105223), a pharmacopoeial impurity reference standard (molecular formula C22H29FN3O9P, MW 529.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Sofosbuvir Impurity 23 (C22H29FN3O9P) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.5, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 529.45 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Sofosbuvir Impurity 23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H29FN3O9P |
| Molecular Weight | 529.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Sofosbuvir Standards
- Sofosbuvir (CAS 1190307-88-0)
- Sofosbuvir Impurity 22 (CAS 1190308-01-0)
- Sofosbuvir Impurity 24 (CAS CATO-C4X-105224)
- Sofosbuvir Impurity 25 (CAS CATO-C4X-105225)
- Sofosbuvir Impurity 26 (CAS CATO-C4X-105226)
- Sofosbuvir Impurity 27 (CAS CATO-C4X-105227)
- Sofosbuvir Impurity 28 (CAS CATO-C4X-105228)
- Sofosbuvir Impurity 29 (CAS CATO-C4X-105229)
Recommended Standards
- (S)-(((2R,3R,4R,5R)-D-Sofosbuvir Isomer (CAS 1496552-28-3)
- D-Alanine Sofosbuvir (CAS 1064684-71-4)
- Fluconazole Impurity 55 (CAS CATO-C4X-101955)
- Fluconazole Impurity 47 (CAS CATO-C4X-101947)
- Salbutamol Impurity 216 (CAS CATO-C4X-1176216)
- Dexmedetomidine Impurity 13 (CAS 104245-83-2)
- CAS CATO-C4X-32403 (CAS CATO-C4X-32403)
- 2-(2-Chlorophenoxy)-2-methylpropanoic acid (CAS 17413-79-5)
- 4-(Trifluoromethyl)benzo[b]thiophene (CAS 120568-06-1)
- 7-Acetyl-5-bromoindolin-2-one (CAS 2089292-39-5)
- (2E)-3-(4-Ethoxyphenyl)-1-phenylprop-2-en-1-one (CAS 32111-71-0)
- (4-Ethoxytetrahydro-2h-thiopyran-4-yl)methanamine (CAS 1496337-23-5)
- Methyl 3-formyl-1H-pyrrolo[3,2-b]pyridine-5-carboxylate (CAS 1190311-00-2)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
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