3,5-Bis(chloromethyl)-1,2,4-oxadiazole CAS 1194-01-0
| CAS No. | 1194-01-0 |
| Molecular Formula | C4H4Cl2N2O |
| Molecular Weight | 166.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 166.99 g/mol gives 3,5-Bis(chloromethyl)-1,2,4-oxadiazole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3,5-Bis(chloromethyl)-1,2,4-oxadiazole (CAS 1194-01-0) is a high-purity analytical reference standard with the molecular formula C4H4Cl2N2O and a molecular weight of 166.99 g/mol.
The molecular framework of 3,5-Bis(chloromethyl)-1,2,4-oxadiazole (C4H4Cl2N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3,5-Bis(chloromethyl)-1,2,4-oxadiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H4Cl2N2O |
| Molecular Weight | 166.99 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Bis Standards
- 2,5-bis(chloromethyl)-1,3,4-oxadiazole (CAS 541540-90-3)
- (Chloromethyl)dimethylisopropoxysilane (Chloromethyl)isopropoxydimethylsilane 18171-11-4 C1370 (CAS 18171-11-4)
- (Chloromethyl)dimethoxy(vinyl)silane (CAS 1314981-48-0)
- 2-(Chloromethyl)-2,3-dihydro-1h-indene (CAS 1260801-96-4)
- 5-(Chloromethyl)-2,3-dihydro-1H-indene (CAS 18775-42-3)
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Recommended Standards
- (5-Cyano-4-methylthiophen-2-yl)boronic acid (CAS 1119899-50-1)
- 4,5-Dichloro-1-hydroxymethylimidazole (CAS 119552-43-1)
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- (5-Cyano-2-methylthiophen-3-yl)boronic acid (CAS 1310384-25-8)
- 2-(3-Chlorophenyl)-6-(pyrrolidin-1-yl)quinazolin-4(3H)-one (CAS 299898-01-4)
- 4-Cyclopropylmethoxy-2-fluoro-benzonitrile (CAS 1369882-54-1)
- 6-(3,4-Dimethoxyphenyl)-3,5-dimethylimidazo[2,1-b]thiazole-2-carboxylic acid (CAS 1181346-34-8)
- 5α-Androstane-3β,17β-diol-d3 (CAS 79037-32-4)
- 3-Hydroxycyclopent-2-en-1-one (CAS 5870-62-2)
- 2-(Aminomethyl)-4-bromoaniline (CAS 771583-12-1)
- Potassium Trifluoro(3-methoxybenzyl)borate (CAS 1569524-37-3)
- Methyl 3-cyanopyridine-2-carboxylate (CAS 53940-11-7)
- Methyl 7-phenylcarbamoylheptanate, 98% (CAS 162853-41-0)
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