2-(3-Chlorophenyl)-6-(pyrrolidin-1-yl)quinazolin-4(3H)-one CAS 299898-01-4
| CAS No. | 299898-01-4 |
| Molecular Formula | C18H16ClN3O |
| Molecular Weight | 325.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(3-Chlorophenyl)-6-(pyrrolidin-1-yl)quinazolin-4(3H)-one.
2-(3-Chlorophenyl)-6-(pyrrolidin-1-yl)quinazolin-4(3H)-one (CAS 299898-01-4) is a high-purity analytical reference standard with the molecular formula C18H16ClN3O and a molecular weight of 325.79 g/mol.
2-(3-Chlorophenyl)-6-(pyrrolidin-1-yl)quinazolin-4(3H)-one (C18H16ClN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(3-Chlorophenyl)-6-(pyrrolidin-1-yl)quinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16ClN3O |
| Molecular Weight | 325.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- (4Z)-4-({[(4-chlorophenyl)methyl]amino}methylidene)-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one (CAS 320425-10-3)
- 1-Benzyl-3-[(4-chlorophenyl)methyl]-4-hydroxy-1,2-dihydropyridin-2-one (CAS 477846-41-6)
- 2-(3-Chlorophenyl)-3,6,8-trimethylquinoline-4-carboxylic acid (CAS 895965-50-1)
- 2-(4-Chlorophenyl)-3,6,8-trimethylquinoline-4-carboxylic acid (CAS 895923-44-1)
- 2-(4-Chlorophenyl)-6-(pyrrolidin-1-yl)quinazolin-4(3H)-one (CAS 299897-98-6)
- 3-(5-(3-Chlorophenyl)furan-2-yl)-N-phenylpropanamide (CAS 853312-43-3)
- 3-(5-(4-Chlorophenyl)furan-2-yl)-N-phenylpropanamide (CAS 853311-43-0)
- 4-((2-Chlorophenyl)amino)-2-(4-methylpiperazin-1-yl)-4-oxobutanoic acid (CAS 540763-74-4)
Recommended Standards
- 1-(Tert-butoxycarbonyl)-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid (CAS 791625-60-0)
- 2-(5-Chloro-8-isopropoxyquinolin-7-yl)benzaldehyde (CAS 648897-06-7)
- 1-(tert-Butoxycarbonyl)-4-(3-chlorophenyl)pyrrolidine-3-carboxylic acid (CAS 939757-91-2)
- 2-Benzyl-4-(benzylamino)-5-chloropyridazin-3(2H)-one (CAS 91736-90-2)
- Benzyl (2-(cyclohexylamino)-2-oxoethyl)carbamate (CAS 3496-41-1)
- Benzyl 2-butyl-4-oxopiperidine-1-carboxylate (CAS 1260773-00-9)
- 2-(5-Cyclobutylpyridin-2-yl)acetic acid hydrochloride (CAS 2197055-45-9)
- (Z)-N'-Hydroxy-3,5-bis(trifluoromethyl)benzimidamide (CAS 1159171-31-9)
- (1-(2,4-Dimethylphenyl)-1H-1,2,3-triazol-4-yl)methanol (CAS 1249435-29-7)
- 1,1,1-Trifluoro-3-(4-fluorophenyl)propan-2-amine (CAS 1737-29-7)
- n-(2-Chloro-5-iodophenyl)-2-methoxypropanamide (CAS 1423801-27-7)
- Methyl 2-(3-(3-fluoro-4-methylbenzoyl)-2-(4-fluorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate (CAS 617697-95-7)
- 2,5-Dimethyl-4-[(morpholin-4-yl)methyl]phenyl 4-chlorobenzene-1-sulfonate hydrochloride (CAS 1049729-81-8)
- Semaglutide impurity 99 (CAS CATO-C4X-222699)
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