Loratadine Methanone Impurity CAS 119770-60-4
| CAS No. | 119770-60-4 |
| Molecular Formula | C20H23ClN2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Loratadine Methanone Impurity (CAS 119770-60-4) is a certified pharmaceutical impurity reference standard with the molecular formula C20H23ClN2OHCl and a molecular weight of 379.32 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Loratadine Methanone Impurity is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 379.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Loratadine Methanone Impurity under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H23ClN2O HCl |
| Molecular Weight | 379.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Loratadine Standards
- Loratadine EP Impurity D (CAS 100643-71-8)
- Loratadine-d5 (CAS 1020719-57-6)
- Loratadine Impurity N9 (CAS 107256-32-6)
- Loratadine Impurity 53 (CAS 107285-30-3)
- Loratadine Impurity 28 (CAS 1073332-71-4)
- Loratadine Epoxide (CAS 1189694-51-6)
- Loratadine EP Impurity F (CAS 125743-80-8)
- Loratadine Impurity 29 (CAS 125743-81-9)
Recommended Standards
- Gadopiclenol Impurity 5 (CAS CATO-C4X-30025)
- Mepivacaine Hydrochloride EP Impurity B (CAS 27262-43-7)
- Troxerutin Impurity 10 (CAS CATO-C4X-280010)
- Vericiguat impurity 48 (CAS CATO-C4X-289648)
- Dexrazoxane Impurity 9 (CAS CATO-C4X-20209)
- trans-2-(4-n-Pentylbenzoyl)cyclopentane-1-carboxylic acid (CAS 733741-10-1)
- Cycloheptanone oxime (CAS 2158-31-8)
- tert-butyl N-tert-butoxycarbonyl-N-(2,6-dichloro-3-fluoro-4-pyridyl)carbamate (CAS 2763157-85-1)
- 9,10-Di-p-tolylanthracene (CAS 43217-31-8)
- [Glu]17-Liraglutide (CAS CATO-C4X-199236)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com