Losartan Impurity 20 CAS 154709-19-0
| CAS No. | 154709-19-0 |
| Molecular Formula | C14H11NO |
| Molecular Weight | 209.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Losartan Impurity 20.
As a process- or degradation-related impurity, Losartan Impurity 20 (CAS 154709-19-0, C14H11NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Losartan Impurity 20 (C14H11NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 209.24 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Losartan Impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H11NO |
| Molecular Weight | 209.24 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Nitrogen Atoms | 1 |
Related Losartan Standards
- Losartan Impurity 63 (CAS CATO-C4X-168363)
- Losartan Impurity 1 (CAS 79047-41-9)
- Losartan EP Impurity D (CAS 83857-96-9)
- Losartan Potassium EP Impurity E (CAS 120568-11-8)
- Losartan EP Impurity B (CAS 160514-13-6)
- Losartan Impurity 18 (CAS 158365-99-2)
- Losartan Impurity 23 (CAS 193140-43-1)
- Losartan Impurity 42 (CAS 2901098-91-5)
Recommended Standards
- Ketorolac Impurity 34 (CAS CATO-C4X-166934)
- Isoproterenol Impurity 40 (CAS 98496-30-1)
- Norepinephrine Impurity 36 (CAS 121-28-8)
- Cabozantinib Impurity 16 (CAS 95932-39-1)
- Abrocitinib Impurity 3 (CAS 2204280-33-9)
- Roxatidine impurity 70 (CAS CATO-C4X-121370)
- Norepinephrine impurity 88 HCl (CAS CATO-C4X-151488)
- 2H-Imidazo[4,5-g]quinoxaline (CAS 27197-64-4)
- 5-(Isopropoxymethyl)-2-isopropyl-5-methyl-1,3-dioxane (CAS 22644-54-8)
- 2-Bromo-3,5-dichlorothiophene (CAS 1536984-16-3)
- N-(2-Bromo-4-methoxyphenyl)acrylamide (CAS 116707-97-2)
- 2-(4-(3-Chlorophenyl)-1H-pyrazol-1-yl)butanoic acid (CAS 1394022-24-2)
- 1-Methylpyrrolo[1,2-a]pyrazine (CAS 64608-59-9)
- Semaglutide Impurity 150 xTFA (CAS CATO-C4X-2226150)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com