Chlorphenamine EP Impurity B CAS 1202-34-2
| CAS No. | 1202-34-2 |
| Molecular Formula | C10H9N3 |
| Molecular Weight | 171.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 171.20 g/mol gives Chlorphenamine EP Impurity B distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Chlorphenamine EP Impurity B (CAS 1202-34-2) is a certified pharmaceutical impurity reference standard with the molecular formula C10H9N3 and a molecular weight of 171.20 g/mol.
The molecular framework of Chlorphenamine EP Impurity B (C10H9N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Chlorphenamine EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9N3 |
| Molecular Weight | 171.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
Related Chlorphenamine Standards
- Chlorphenamine Impurity 6 (CAS 20101-92-2)
- Chlorphenamine Impurity 31 (CAS 5005-36-7)
- Chlorphenamine Impurity 20 (CAS 4350-41-8)
- Chlorphenamine Impurity 72 (CAS CATO-C4X-118872)
- Chlorphenamine impurity 56 (CAS CATO-C4X-118856)
- Chlorphenamine Impurity 21 (CAS 5005-37-8)
- Chlorphenamine Impurity 25 (CAS 122376-68-5)
- Chlorphenamine impurity 58 (CAS 123517-65-7)
Recommended Standards
- Vonoprazan Impurity 36 (CAS 56448-22-7)
- Ketorolac Impurity 36 (CAS 7697-46-3)
- N-(1-Nitrosopiperidin-3-yl)Acetamide (CAS CATO-C3D-26132)
- Upadacitinib Impurity 142 (CAS CATO-C4X-2405142)
- Perindopril EP Impurity I（Enantiomer Mixture）tert-Butylamine Salt (CAS 145513-33-3(free base))
- (S)-Baxdrostat Impurity 25 (CAS 1428652-36-1)
- Finerenone Impurity 111 (CAS CATO-C4X-2880111)
- methyl 1-(N6-(tert-butoxycarbonyl)-D-lysyl)-4-((tert-butoxycarbonyl)amino)piperidine-4-carboxylate (CAS 1821319-24-7)
- Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate (CAS 2490681-47-3)
- tert-Butyl 6-amino-3-((diethylamino)methyl)-1H-indazole-1-carboxylate (CAS 887590-89-8)
- Dimethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2,6-dicarboxylate (CAS 741709-66-0)
- 2,4-Dichloro-7-methylpyrrolo[2,1-f][1,2,4]triazine (CAS 1613751-73-7)
- 1,3-Diiodo-2,2-dimethylpropane (CAS 66688-49-1)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
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