(R)-2-Amino-4,4,4-trifluorobutanoic acid CAS 120200-07-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-2-Amino-4,4,4-trifluorobutanoic acid.

(R)-2-Amino-4,4,4-trifluorobutanoic acid (CAS 120200-07-9) is a high-purity analytical reference standard with the molecular formula C4H6F3NO2 and a molecular weight of 157.09 g/mol.

(R)-2-Amino-4,4,4-trifluorobutanoic acid (C4H6F3NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (R)-2-Amino-4,4,4-trifluorobutanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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