2-Amino-3,3,3-trifluoro-2-methylpropanoic acid CAS 422-23-1
| CAS No. | 422-23-1 |
| Molecular Formula | C4H6F3NO2 |
| Molecular Weight | 157.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-3,3,3-trifluoro-2-methylpropanoic acid.
2-Amino-3,3,3-trifluoro-2-methylpropanoic acid (CAS 422-23-1) is a high-purity analytical reference standard with the molecular formula C4H6F3NO2 and a molecular weight of 157.09 g/mol.
The molecular framework of 2-Amino-3,3,3-trifluoro-2-methylpropanoic acid (C4H6F3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Amino-3,3,3-trifluoro-2-methylpropanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H6F3NO2 |
| Molecular Weight | 157.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- 2-amino-3,3,3-trifluoro-2-methylpropanoic acid (CAS 102210-02-6)
- (S)-2-Amino-3,3,3-trifluoro-2-methylpropanoic acid (CAS 102210-03-7)
- 3-amino-1-(2,2,2-trifluoroethyl)urea (CAS 1094561-65-5)
- (R)-2-Amino-4,4,4-trifluorobutanoic acid (CAS 120200-07-9)
- (S)-3-Amino-4,4,4-trifluorobutanoic acid (CAS 151871-99-7)
- (R)-3-amino-4,4,4-trifluorobutanoic acid (CAS 151911-19-2)
- 2-Amino-4,4,4-trifluorobutyric acid (CAS 15959-93-0)
- (S)-2-Amino-4,4,4-trifluorobutanoic acid (CAS 15960-05-1)
Recommended Standards
- 2,4,6-Trifluorobenzonitrile (CAS 96606-37-0)
- 3-Amino-4,4,4-trifluorobutyric acid (CAS 584-20-3)
- 2,4,5-Trifluorobenzonitrile (CAS 98349-22-5)
- 3-Nitro-1H-1,2,4-triazole-5-carboxamide (CAS 199292-34-7)
- (R)-3-Amino-1-phenylpropan-1-ol hydrochloride (CAS 200621-69-8)
- 3-Ethyl-N-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboximidamide (CAS 791722-16-2)
- N-(4-(4-(Phenylsulfonyl)piperidine-1-carbonyl)phenyl)acetamide (CAS 1448063-34-0)
- Methyl (R)-2-hydroxypent-4-enoate (CAS 96488-05-0)
- (E)-4-Chloro-3-(5-(2-nitrovinyl)furan-2-yl)benzoic acid (CAS 359618-41-0)
- Ruxolitinib Impurity 13 (CAS 1865785-69-8)
- 1-Butyl-1,4-dihydroquinoxaline-2,3-dione (CAS 1206077-97-5)
- 4-Chloro-1-ethyl-3-iodo-6-methylpyridin-2(1H)-one (CAS 1708250-50-3)
- 4-[(3,5-Dimethyl-1H-pyrazol-1-yl)methyl]piperidine (CAS 1211498-15-5)
- Insulin Degludec Impurity 14 (CAS CATO-C4X-215714)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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