Diclofenac Impurity 60 CAS 120339-20-0
| CAS No. | 120339-20-0 |
| Molecular Formula | C17H17Cl2NO3 |
| Molecular Weight | 354.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Diclofenac Impurity 60 (CAS 120339-20-0) is a certified pharmaceutical impurity reference standard with the molecular formula C17H17Cl2NO3 and a molecular weight of 354.23 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Diclofenac Impurity 60 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 354.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Diclofenac Impurity 60 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H17Cl2NO3 |
| Molecular Weight | 354.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Diclofenac Standards
- Diclofenac Impurity 27 (CAS CATO-C4X-105127)
- Diclofenac Impurity 28 (CAS CATO-C4X-105128)
- Diclofenac EP Impurity D Sodium Salt (CAS 127792-45-4)
- Diclofenac Impurity 8 (CAS 106610-60-0)
- Diclofenac N-Oxydiethylamine Ester (CAS CATO-C4X-16142)
- Diclofenac EP Impurity D (CAS 127792-23-8)
- Diclofenac Isopropyl Ester (CAS 66370-79-4)
- Diclofenac sodium Impurity 56 (CAS 221016-39-3)
Recommended Standards
- tert-butyl benzyl(2,6-dichloropyrimidin-4-yl)carbamate (CAS 270929-33-4)
- 1-[(5-bromothiophen-2-yl)sulfonyl]piperidine-2-carboxylic acid (CAS 1008571-93-4)
- tert-butyl 6-bromo-4,4-difluoro-2,3-dihydroquinoline-1-carboxylate (CAS 2387599-03-1)
- 4-(4-Bromophenyl)-2-(cyclohexylamino)-4-oxobutanoic acid (CAS 1031263-33-8)
- Vortioxetine Impurity 104 (CAS CATO-C4X-1056104)
- Pranoprofen Impurity 46 (CAS CATO-C4X-181146)
- Terazosin EP Impurity K (CAS 19216-56-9)
- 8-methyl-5,6,7,8-tetrahydropteridin-6-one (CAS 1314964-55-0)
- 3,5-Thiomorpholinedione (CAS 80023-40-1)
- 1-Isopropyl-5-oxo-2-(pyridin-3-yl)pyrrolidine-3-carboxylic acid (CAS 147451-99-8)
- 5-Phenyl-1H-benzo[d]imidazole (CAS 90445-37-7)
- 3-(Diethylamino)-1,2-dihydroquinoxalin-2-one (CAS 731795-58-7)
- 2-(3,3-Diethoxyprop-1-yn-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 159087-48-6)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com