Diclofenac Impurity 28 CAS CATO-C4X-105128
| CAS No. | CATO-C4X-105128 |
| Molecular Formula | C14H9Cl4NO |
| Molecular Weight | 349.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Diclofenac Impurity 28 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Diclofenac Impurity 28 (CAS CATO-C4X-105128) is a certified pharmaceutical impurity reference standard with the molecular formula C14H9Cl4NO and a molecular weight of 349.04 g/mol.
Based on its molecular formula C14H9Cl4NO, Diclofenac Impurity 28 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 349.04 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Diclofenac Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9Cl4NO |
| Molecular Weight | 349.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Diclofenac Standards
- Diclofenac Impurity 27 (CAS CATO-C4X-105127)
- Diclofenac Impurity 60 (CAS 120339-20-0)
- Diclofenac Impurity 8 (CAS 106610-60-0)
- Diclofenac EP Impurity D (CAS 127792-23-8)
- Diclofenac Isopropyl Ester (CAS 66370-79-4)
- Diclofenac EP Impurity D Sodium Salt (CAS 127792-45-4)
- Diclofenac N-Oxydiethylamine Ester (CAS CATO-C4X-16142)
- Diclofenac impurity 9 (CAS CATO-C4X-16149)
Recommended Standards
- Methyl 2-[3-bromo-4-(trifluoromethoxy)phenyl]-2,2-difluoroacetate (CAS 1820712-80-8)
- 2-Bromo-4-(4-bromo-3-methoxyphenyl)thiazole (CAS 886367-70-0)
- 1,3-Dibromodithieno[3,4-b:3',2'-d]pyridine (CAS 153776-41-1)
- 6-Bromo-4-(trifluoromethoxy)-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 1417341-58-2)
- Posaconazole impurity 237 (CAS CATO-C4X-1208237)
- Amoxicillin Impurity 64 (CAS CATO-C4X-114864)
- Meclofenoxate Impurity 3 (CAS CATO-C4X-24693)
- (2-Methylquinolin-4-yl)(piperazin-1-yl)methanone (CAS 63591-79-7)
- 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate (CAS 313223-04-0)
- 4-(Pyrrolidin-1-yl)benzenesulfonyl chloride (CAS 125393-18-2)
- 1-(bromomethyl)-2-methyl-cyclopropane (CAS 31950-58-0)
- 5,8-Dibromo-2,3-bis[3-(octyloxy)phenyl]quinoxaline (CAS 565228-31-1)
- 2-((4,6-Dimethylpyrimidin-2-yl)thio)propan-1-amine (CAS 1248098-95-4)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com