Icotinib Impurity 5 CAS 1204313-58-5
| CAS No. | 1204313-58-5 |
| Molecular Formula | C14H15ClN2O4 |
| Molecular Weight | 310.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Icotinib Impurity 5 (CAS 1204313-58-5), a pharmacopoeial impurity reference standard (molecular formula C14H15ClN2O4, MW 310.73 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C14H15ClN2O4, Icotinib Impurity 5 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 310.73 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Icotinib Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H15ClN2O4 |
| Molecular Weight | 310.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Icotinib Standards
Recommended Standards
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- Sibutramine Impurity 6 (CAS 2758418-79-8)
- 4-Chloro-5-methylpyridin-3-ol (CAS 1261269-38-8)
- Selexipag RC 3 (CAS 2514706-51-3)
- Ethyl 2-amino-3-ethoxy-6-fluorobenzoate (CAS 1341578-95-7)
- 4-Bromo-2-chloro-6-(chloromethyl)pyridine (CAS 1393554-93-2)
- 3-Bromo-2-methoxytetrahydro-2H-pyran (CAS 5324-21-0)
- 2-Ethyl-5-(1H-indol-2-yl)-1,3,4-thiadiazole (CAS 757213-72-2)
- Des-Gly29,30-Tirzepatide (CAS CATO-CPTD788944)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com