Safinamide Impurity 17 CAS 1205608-96-3
| CAS No. | 1205608-96-3 |
| Molecular Formula | C14H13FO |
| Molecular Weight | 216.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Safinamide Impurity 17 (C14H13FO) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Safinamide Impurity 17 (CAS 1205608-96-3) is a certified pharmaceutical impurity reference standard with the molecular formula C14H13FO and a molecular weight of 216.25 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H13FO |
| Molecular Weight | 216.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Safinamide Standards
- Safinamide Impurity 20 (CAS 4397-53-9)
- Safinamide impurity 01 (CAS 1443302-79-1)
- Safinamide Impurity 18 (CAS 56442-17-2)
- Safinamide Impurity 19 (CAS 70627-20-2)
- Safinamide Impurity 21 (CAS 590353-54-1)
- Safinamide Impurity 44 (CAS 172685-67-5)
- Safinamide Impurity 5 (CAS 690969-16-5)
- Safinamide Impurity 23 (CAS CATO-C4X-159023)
Recommended Standards
- Doxofylline Impurity 18 (CAS 42772-85-0)
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- Menaquinone Impurity 4 (CAS 72908-86-2)
- Daptomycin Impurity 6 (CAS CATO-C4X-13786)
- Dolutegravir Impurity 43 (CAS 2651309-06-5)
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- 3-Methyl-1-heptanol, 97% (CAS 1070-32-2)
- 1-Ethyl-5-(hydrazinylmethyl)-1h-imidazole (CAS 1462241-74-2)
- Mast Cell Degranulating (MCD) Peptide (CAS 32908-73-9)
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