Safinamide Impurity 21 CAS 590353-54-1
| CAS No. | 590353-54-1 |
| Molecular Formula | C14H11FO2 |
| Molecular Weight | 230.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Safinamide Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Safinamide Impurity 21 (CAS 590353-54-1, C14H11FO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C14H11FO2, Safinamide Impurity 21 contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 230.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H11FO2 |
| Molecular Weight | 230.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
Related Safinamide Standards
- Safinamide impurity 01 (CAS 1443302-79-1)
- Safinamide Impurity 18 (CAS 56442-17-2)
- Safinamide Impurity 19 (CAS 70627-20-2)
- Safinamide Impurity 44 (CAS 172685-67-5)
- Safinamide Impurity 5 (CAS 690969-16-5)
- Safinamide Impurity 17 (CAS 1205608-96-3)
- Safinamide Impurity 33 (CAS 405-85-6)
- Safinamide Impurity 20 (CAS 4397-53-9)
Recommended Standards
- Etrasimod Impurity 77 (CAS CATO-C4X-321477)
- Flurbiprofen Impurity 84 (CAS 5001-96-7)
- 4-Ethyl-3-nitrobenzenesulfonamide (CAS 100377-77-3)
- Pantoprazole Impurity 77 (CAS CATO-C4X-139977)
- Vericiguat Impurity 91 (CAS CATO-C4X-289691)
- Telmisartan Impurity 22 (CAS 1797894-62-2)
- Sivelestat sodium impurity 22 (CAS 1655497-02-1)
- 6-Bromo-4-methoxy-2-(trifluoromethyl)quinoline (CAS 882292-61-7)
- 3-ethynyl-3-methoxyoxolane (CAS 2168729-64-2)
- 1-[(3,4-Dichlorophenyl)methyl]-4-nitro-1h-pyrazole (CAS 333444-52-3)
- Ethylene-d4-diamine-1-N-t-BOC (CAS 509148-73-6)
- 6-Amino-1-isopropylindoline (CAS 927684-86-4)
- (4-(Azetidin-1-ylmethyl)phenyl)(2,4-dimethylphenyl)methanone (CAS 898756-61-1)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com