Doxofylline Impurity 18 CAS 42772-85-0
| CAS No. | 42772-85-0 |
| Molecular Formula | C9H12O4S |
| Molecular Weight | 216.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Doxofylline Impurity 18.
CATO supplies Doxofylline Impurity 18 (CAS 42772-85-0), a pharmacopoeial impurity reference standard (molecular formula C9H12O4S, MW 216.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C9H12O4S, Doxofylline Impurity 18 contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 216.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H12O4S |
| Molecular Weight | 216.25 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Sulfur Atoms | 1 |
Related Doxofylline Standards
- Doxofylline Impurity 2 (CAS 5614-53-9)
- Doxofylline Impurity 9 (CAS CATO-C4X-15139)
- Doxofylline Impurity 33 (CAS CATO-C4X-151333)
- Doxofylline Impurity 35 (CAS CATO-C4X-151335)
- Doxofylline Impurity 10 (CAS CATO-C4X-151310)
- Doxofylline Impurity 32 (CAS 633296-51-2)
- Doxofylline Impurity 40 (CAS 23146-07-8)
- Doxofylline Impurity 20 (CAS 1021-65-4)
Recommended Standards
- Flurbiprofen Impurity 37 (CAS 56430-67-2)
- Safinamide Impurity 17 (CAS 1205608-96-3)
- 4-Hydroxy-2,3,5-trimethylbenzenesulfonic acid (CAS 40764-21-4)
- Salicylic Acid Impurity 17 (CAS 870806-51-2)
- Cefamandole Impurity 20 (CAS CATO-C4X-122120)
- Ibandronic Impurity 14 (CAS 2377035-78-2)
- Vinpocetine Impurity 2 (Oxime) (CAS 102341-40-2)
- 5-Cyclopropylpentanoic acid (CAS 5266-60-4)
- 4-Azaspiro[2.4]hepta-1,4,6-triene (CAS 926283-34-3)
- 2-(Difluoromethyl)-6-iodo-3-(trifluoromethoxy)pyridine-4-acetonitrile (CAS 1804859-01-5)
- (2-aminoethyl)[(propan-2-yl)sulfamoyl]amine hydrochloride (CAS 1798717-49-3)
- (2-Methoxyethyl)(1-methoxypropan-2-yl)amine (CAS 1021042-07-8)
- N-[4-[N-(3-Chloro-2-quinoxalinyl)sulfamoyl]phenyl]acetamide (CAS 4029-42-9)
- Tirzepatide Impurity 37 (CAS CATO-C4X-324037)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com