5-Fluoropyrimidine-2,4-dicarbonitrile CAS 1208813-28-8
| CAS No. | 1208813-28-8 |
| Molecular Formula | C6HFN4 |
| Molecular Weight | 148.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Fluoropyrimidine-2,4-dicarbonitrile (CAS 1208813-28-8), a certified reference material (molecular formula C6HFN4, MW 148.10 g/mol) for analytical method development and quality control.
Owing to a nitrile group, fluorine substitution, an aromatic ring system, 5-Fluoropyrimidine-2,4-dicarbonitrile is typically pale yellow to yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 148.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Fluoropyrimidine-2,4-dicarbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6HFN4 |
| Molecular Weight | 148.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fluoropyrimidine Standards
- 5-fluoropyrimidine-2-carboxylic acid (CAS 1196151-51-5)
- 5-fluoropyrimidine-4-carboxylic acid (CAS 1211528-24-3)
- 5-Fluoropyrimidine-2,4,6-triol (CAS 767-80-6)
- 6-Fluoropyrimidine-4-carboxylic acid (CAS 1806334-01-9)
- 5-Fluoropyrimidine-2-carboxamide (CAS 1378675-45-6)
- Methyl 5-Fluoropyrimidine-2-carboxylate (CAS 1227575-47-4)
- Methyl 2-fluoropyrimidine-4-carboxylate (CAS 1785581-69-2)
- Methyl 4-fluoropyrimidine-2-carboxylate (CAS 1806489-74-6)
Recommended Standards
- Fluorouracil Impurity 11 (Mixture of Diastereomers) (CAS 37103-91-6)
- (E)-3-(Dimethylphosphoryl)acrylic acid (CAS 2920074-81-1)
- 3,5,6-Trifluoropyridin-2-amine (CAS 3534-50-7)
- Imidazoleacetic acid (sodium) (CAS 56368-58-2)
- 5-Tosylquinolin-8-ol (CAS 61430-91-9)
- 1-Bromo-3-ethoxy-2,4-difluorobenzene (CAS 1881291-79-7)
- Isoquinoline-1,7-diamine (CAS 244219-96-3)
- 5-Bromo-2,4-dimethylbenzene-1-sulfonamide (CAS 1206087-06-0)
- tert-Butyl {[1-(pentan-3-yl)piperidin-4-yl]methyl}carbamate (CAS 1286275-01-1)
- (S)-3-((tert-Butoxycarbonyl)amino)-4-(2-cyanophenyl)butanoic acid (CAS 270065-83-3)
- Osimertinib Impurity 90 (CAS CATO-C4X-204590)
- 1-Bromo-4-(2-methylbutan-2-yl)benzene (CAS 57263-21-5)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-2-one (CAS 923143-11-7)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
Why CATO?
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