5-fluoropyrimidine-4-carboxylic acid CAS 1211528-24-3
| CAS No. | 1211528-24-3 |
| Molecular Formula | C5H9FN2O2 |
| Molecular Weight | 148.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-fluoropyrimidine-4-carboxylic acid (CAS 1211528-24-3), molecular formula C5H9FN2O2 and molecular weight 148.14 g/mol, is a CATO reference standard with documented purity and traceability.
5-fluoropyrimidine-4-carboxylic acid (C5H9FN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-fluoropyrimidine-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H9FN2O2 |
| Molecular Weight | 148.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related fluoropyrimidine Standards
- 5-fluoropyrimidine-2-carboxylic acid (CAS 1196151-51-5)
- 5-Fluoropyrimidine-2,4-dicarbonitrile (CAS 1208813-28-8)
- 5-Fluoropyrimidine-2,4,6-triol (CAS 767-80-6)
- 6-Fluoropyrimidine-4-carboxylic acid (CAS 1806334-01-9)
- 5-Fluoropyrimidine-2-carboxamide (CAS 1378675-45-6)
- Methyl 5-Fluoropyrimidine-2-carboxylate (CAS 1227575-47-4)
- Methyl 2-fluoropyrimidine-4-carboxylate (CAS 1785581-69-2)
- Methyl 4-fluoropyrimidine-2-carboxylate (CAS 1806489-74-6)
Recommended Standards
- 4-fluoro-1-methyl-1H-pyrazole-3-carboxylic acid (CAS 1198437-08-9)
- 5-Fluorocinnoline (CAS 1309379-23-4)
- 2-Fluoro-1,5-naphthyridine (CAS 1309379-24-5)
- 5-Fluorophthalazine (CAS 103119-77-3)
- 4-(tert-Butyl)phenyl 4-piperidinylmethyl etherhydrochloride (CAS 1185304-13-5)
- 3-Bromo-2-oxopropyl acetate (CAS 130335-46-5)
- N-(5-Cyclopropyl-1H-pyrazol-3-yl)formamide (CAS 845816-40-2)
- 2-Bromo-1-(4-ethylpyridin-3-yl)ethanone (CAS 757180-99-7)
- N-Cyclohexyl-5-methyl-3-(p-tolyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 890611-94-6)
- Ethyl 2-methylbut-3-enoate (CAS 1647-12-7)
- 2-(4-Chlorophenyl)-2-(phenethylamino)acetonitrile (CAS 1018527-41-7)
- Rel-tert-butyl ((1r,4r)-4-ethoxycyclohexyl)carbamate (CAS 952302-07-7)
- Erlotinib Impurity 47 (CAS 179688-26-7)
- Semaglutide impurity 235 (CAS CATO-C4X-2226235)
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