Methyl 2-fluoropyrimidine-4-carboxylate CAS 1785581-69-2
| CAS No. | 1785581-69-2 |
| Molecular Formula | C6H5FN2O2 |
| Molecular Weight | 156.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Methyl 2-fluoropyrimidine-4-carboxylate (CAS 1785581-69-2), a certified reference material (molecular formula C6H5FN2O2, MW 156.11 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Methyl 2-fluoropyrimidine-4-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 156.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H5FN2O2 |
| Molecular Weight | 156.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- Methyl 5-Fluoropyrimidine-2-carboxylate (CAS 1227575-47-4)
- Methyl 4-fluoropyrimidine-2-carboxylate (CAS 1806489-74-6)
- 3-Ethyl-5-fluoropyrimidine-2,4(1H,3H)-dione (CAS 192625-76-6)
- 5-fluoropyrimidine-2-carboxylic acid (CAS 1196151-51-5)
- 5-fluoropyrimidine-4-carboxylic acid (CAS 1211528-24-3)
- 5-Fluoropyrimidine-2,4-dicarbonitrile (CAS 1208813-28-8)
- 5-Fluoropyrimidine-2,4,6-triol (CAS 767-80-6)
- 6-Fluoropyrimidine-4-carboxylic acid (CAS 1806334-01-9)
Recommended Standards
- 3-Fluoro-5-methyl-4-nitropyridine (CAS 1784408-72-5)
- 2-Fluoro-5-methyl-4-nitropyridine (CAS 1803825-71-9)
- 5-Fluoro-2-methyl-4-nitropyridine (CAS 1781990-44-0)
- 3-Fluoro-4-methyl-5-nitropyridine (CAS 1803834-51-6)
- 2-(Chloromethyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide (CAS 935862-81-0)
- TERT-BUTYL 3-(3-AMINOPHENOXY)PIPERIDINE-1-CARBOXYLATE (CAS 1464091-70-0)
- 4-Bromo-2-(2,2,2-trifluoroethyl)pyridine (CAS 1393540-83-4)
- 2-Cyclopropyl-2-methyl-1,3-dioxolane (CAS 766-24-5)
- N-(5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide (CAS 865288-11-5)
- 1-Bromo-2,4-dimethoxy-3-methylbenzene (CAS 22794-95-2)
- (R)-3-Amino-4-(m-tolyl)butanoic acid hydrochloride (CAS 331846-94-7)
- Atorvastatin Impurity 145 (CAS CATO-C4X-1132145)
- 3-Oxocyclohexylboronic Acid Pinacol Ester (CAS 302577-72-6)
- Semaglutide Impurity 180 (CAS CATO-C4X-2226180)
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