1-Boc-3,3-difluoropiperidin-4-ol CAS 1209780-71-1
| CAS No. | 1209780-71-1 |
| Molecular Formula | C10H17F2NO3 |
| Molecular Weight | 237.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Boc-3,3-difluoropiperidin-4-ol.
CATO supplies 1-Boc-3,3-difluoropiperidin-4-ol (CAS 1209780-71-1), a certified reference material (molecular formula C10H17F2NO3, MW 237.24 g/mol) for analytical method development and quality control.
The molecular framework of 1-Boc-3,3-difluoropiperidin-4-ol (C10H17F2NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Boc-3,3-difluoropiperidin-4-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H17F2NO3 |
| Molecular Weight | 237.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Boc Standards
- 2-(4,4-Difluoropiperidin-1-yl)-2-phenylacetonitrile (CAS 1226998-22-6)
- 1-Boc-4,4-difluoropiperidin-3-amine (CAS 1283718-72-8)
- 5-(4,4-Difluoropiperidin-1-yl)-1H-indole (CAS 1779128-05-0)
- 2-(4,4-Difluoropiperidin-1-yl)-2-phenylethanamine (CAS 1227040-43-8)
- (1-Benzyl-4,4-difluoropiperidin-3-yl)methanol (CAS 1303973-25-2)
- (1-Benzyl-3,3-difluoropiperidin-4-yl)methanol (CAS 1303974-07-3)
- (4,4-Difluoropiperidin-1-yl)(piperidin-4-yl)methanone (CAS 1442474-22-7)
- 4-(4,4-Difluoropiperidin-1-yl)-2-methoxyphenylamine (CAS 1233184-63-8)
Recommended Standards
- (2S,4S)-tert-Butyl 2-(difluoromethyl)-4-hydroxypyrrolidine-1-carboxylate (CAS 1207852-93-4)
- (r)-2-Amino-2-(3-((trifluoromethyl)thio)phenyl)ethan-1-ol (CAS 1213870-97-3)
- tert-Butyl 4,4-difluoro-3-hydroxypiperidine-1-carboxylate (CAS 1186688-52-7)
- tert-Butyl N-[3,3-difluoro-1-(hydroxymethyl)cyclobutyl]carbamate (CAS 1232365-42-2)
- (R)-Phenprocoumon (CAS 599-27-9)
- 3-((5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl)thio)propanoic acid (CAS 890594-70-4)
- 4-(Difluoromethylene)piperidine hydrochloride (CAS 208245-66-3)
- 2-Chloro-4-(methylsulfonyl)-N-(4-morpholinophenyl)benzamide (CAS 250714-54-6)
- 4-(4-Isobutylphenyl)cyclohexanone (CAS 1890662-66-4)
- 3-(Phenylthio)-N-(5-(thiophen-2-ylmethyl)-1,3,4-oxadiazol-2-yl)propanamide (CAS 1049174-68-6)
- 2-((2-Aminothiazol-4-yl)methyl)-1,3,2-dioxaphosphinane 2-oxide methanesulfonate (CAS 2173153-42-7)
- (2S,3S)-N-(2-Methoxybenzyl)-2-phenylpiperidin-3-amine dihydrochloride (CAS 145148-39-6)
- Pyridoxine impurity 88 (CAS CATO-C4X-187788)
- Tirzepatide Impurity 57 (CAS CATO-C4X-324057)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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