(4,4-Difluoropiperidin-1-yl)(piperidin-4-yl)methanone CAS 1442474-22-7
| CAS No. | 1442474-22-7 |
| Molecular Formula | C11H18F2N2O |
| Molecular Weight | 232.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 232.27 g/mol gives (4,4-Difluoropiperidin-1-yl)(piperidin-4-yl)methanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(4,4-Difluoropiperidin-1-yl)(piperidin-4-yl)methanone (CAS 1442474-22-7) is a high-purity analytical reference standard with the molecular formula C11H18F2N2O and a molecular weight of 232.27 g/mol.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (4,4-Difluoropiperidin-1-yl)(piperidin-4-yl)methanone is typically white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 232.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H18F2N2O |
| Molecular Weight | 232.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoropiperidin Standards
- 2-(4,4-Difluoropiperidin-1-yl)-2-phenylacetonitrile (CAS 1226998-22-6)
- 1-Boc-4,4-difluoropiperidin-3-amine (CAS 1283718-72-8)
- 5-(4,4-Difluoropiperidin-1-yl)-1H-indole (CAS 1779128-05-0)
- 1-Boc-3,3-difluoropiperidin-4-ol (CAS 1209780-71-1)
- 1-Benzyl-3,3-difluoropiperidin-4-ol (CAS 1239596-53-2)
- 1-Benzyl-3,3-difluoropiperidin-4-amine (CAS 1039741-55-3)
- 5-(4,4-Difluoropiperidin-1-yl)picolinaldehyde (CAS 1707365-72-7)
- 5-(3,3-Difluoropiperidin-1-yl)nicotinaldehyde (CAS 1707581-12-1)
Recommended Standards
- (1S)-1-((3aR,4R,6aR)-6-methoxy-2,2,6a-trimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)ethan-1-ol (CAS 1417563-73-5)
- tert-Butyl 3-(2-(2-oxoethoxy)ethoxy)propanoate (CAS 1491136-22-1)
- (1R)-1-((3aR,4R,6aR)-6-methoxy-2,2,6a-trimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)ethan-1-ol (CAS 1417563-64-4)
- 1-(2-Fluorophenyl)-2-(methylsulfonyl)propan-1-ol (CAS 1600335-76-9)
- Tert-butyl (R)-3-(1-amino-2-methoxy-2-oxoethyl)azetidine-1-carboxylate (CAS 2199213-93-7)
- 6-Bromo-8-methylthioimidazo[1,2-a]pyrazinamine (CAS 887475-71-0)
- 2-Bromo-1-chloro-4-(methoxymethoxy)benzene (CAS 2635937-36-7)
- Ethyl 5-acetamido-4-cyano-3-methylthiophene-2-carboxylate (CAS 23903-49-3)
- 2-Fluoro-L-tyrosine hydrochloride (CAS 2097073-16-8)
- 3-[3-Ethyl-1-(4-isopropylphenyl)-1H-1,2,4-triazol-5-yl]propanoic acid (CAS 1142202-64-9)
- n-{3-[1-(methylamino)ethyl]phenyl}benzamide (CAS 923783-95-3)
- N-(5-Aminopyrimidin-2-yl)acetamide (CAS 59690-85-6)
- YM-26734 (CAS 144337-18-8)
- Des-Ala35-Tirzepatide (CAS CATO-CPTD788939)
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