8-Chloro-6-(pyridin-4-yl)-1,7-naphthyridine CAS 1211595-29-7
| CAS No. | 1211595-29-7 |
| Molecular Formula | C13H8ClN3 |
| Molecular Weight | 241.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 8-Chloro-6-(pyridin-4-yl)-1,7-naphthyridine (C13H8ClN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 8-Chloro-6-(pyridin-4-yl)-1,7-naphthyridine (CAS 1211595-29-7), a certified reference material (molecular formula C13H8ClN3, MW 241.68 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-Chloro-6-(pyridin-4-yl)-1,7-naphthyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H8ClN3 |
| Molecular Weight | 241.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 1-Chloro-3-(pyridin-4-yl)-2,6-naphthyridine (CAS 1071017-49-6)
- 1-Chloro-3-(pyridin-4-yl)-2,7-naphthyridine (CAS 1211593-56-4)
- 5-Chloro-2-(pyridin-3-yl)-1,6-naphthyridine (CAS 1443286-75-6)
- 2-Chloro-3-(2-pyridinyl)quinoxaline (CAS 7755-94-4)
- 2-chloro-6-(trifluoromethyl)quinoline (CAS 78060-56-7)
- 4-Chloro-2-(3-pyridyl)quinazoline (CAS 98296-25-4)
- 4-chloro-2-(pyridin-2-yl)quinazoline (CAS 91748-47-9)
- 4-Chloro-2-(pyridin-4-yl)quinazoline (CAS 6484-27-1)
Recommended Standards
- Pyrido[1,2-a]benzimidazole-4-carbonitrile, 1-chloro-3-methyl- (CAS 121105-78-0)
- Lornoxicam Impurity N1 (CAS 1017791-22-8)
- Palbociclib Impurity 197 (CAS 1314997-73-3)
- Baclofen Impurity 41 (CAS 159156-84-0)
- 1-[[3,5-Bis(trifluoromethyl)phenyl]diselanyl]-3,5-bis(trifluoromethyl)benzene (CAS 335383-23-8)
- N6,N6-Dimethyl-1H-indazole-5,6-diamine (CAS 1499162-43-4)
- Ethyl 3-(3-bromophenyl)-2,2-dimethylpropanoate (CAS 1149357-69-6)
- 4-((2,4-Dichlorobenzyl)oxy)aniline (CAS 53397-81-2)
- 1-(4-Bromo-2-nitrophenoxy)propan-2-one (CAS 1254332-83-6)
- 3-(Cyclohexylamino)benzo[d]isothiazole 1,1-dioxide (CAS 7668-22-6)
- 2-(Isopropylimino)cyclopentanone (CAS 62041-55-8)
- 2-Methyl-2,3-dihydro-1-benzofuran-5-sulfonamide (CAS 1343576-63-5)
- 5,6-Dimethylbenzimidazole-2(3H)-thione (CAS 3287-79-4)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com