2-chloro-6-(trifluoromethyl)quinoline CAS 78060-56-7
| CAS No. | 78060-56-7 |
| Molecular Formula | C10H15ClF3N |
| Molecular Weight | 241.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-chloro-6-(trifluoromethyl)quinoline (CAS 78060-56-7), molecular formula C10H15ClF3N and molecular weight 241.68 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-chloro-6-(trifluoromethyl)quinoline (C10H15ClF3N) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-chloro-6-(trifluoromethyl)quinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H15ClF3N |
| Molecular Weight | 241.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- Papaverine-d3 Hydrochloride (CAS 113718-66-4)
- bicyclo[4.2.0]octa-1,3,5,7-tetraen-3-ylboronic acid (CAS 195730-31-5)
- 4-tert-Butylcalix[6]arene (CAS 78092-53-2)
- 2-(((4-Chlorophenyl)thio)methyl)-1H-benzo[d]imidazole (CAS 14483-78-4)
- 4-Ethoxy-3-ethylbenzaldehyde (CAS 883536-96-7)
- [2,7-Di(tert-butyl)-9,9-dimethylxanthene-4,5-diyl]bis(diphenylphosphine) (CAS 221462-97-1)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
Why CATO?
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