2,3-Difluorophenylboronic Acid CAS 121219-16-7

Purity 97%+In StockPharmaceutical Standards
CAS No.121219-16-7
Molecular FormulaC6H5BF2O2
Molecular Weight157.91 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,3-Difluorophenylboronic Acid CAS 121219-16-7 chemical structure

Description

The occurrence of 2,3-Difluorophenylboronic Acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2,3-Difluorophenylboronic Acid (CAS 121219-16-7), molecular formula C6H5BF2O2 and molecular weight 157.91 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2,3-Difluorophenylboronic Acid (C6H5BF2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,3-Difluorophenylboronic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H5BF2O2
Molecular Weight157.91 g/mol
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1991
Halogen ContentF-containing

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