3,4-Difluorophenylboronic Acid CAS 168267-41-2
| CAS No. | 168267-41-2 |
| Molecular Formula | C6H5BF2O2 |
| Molecular Weight | 157.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 157.91 g/mol gives 3,4-Difluorophenylboronic Acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3,4-Difluorophenylboronic Acid (CAS 168267-41-2), molecular formula C6H5BF2O2 and molecular weight 157.91 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3,4-Difluorophenylboronic Acid (C6H5BF2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3,4-Difluorophenylboronic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5BF2O2 |
| Molecular Weight | 157.91 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | F-containing |
Related Difluorophenylboronic Standards
- 2,3-Difluorophenylboronic Acid (CAS 121219-16-7)
- 2,4-Difluorophenylboronic Acid (CAS 144025-03-6)
- 3,5-Difluorophenylboronic Acid (CAS 156545-07-2)
- 2,5-Difluorophenylboronic Acid (CAS 193353-34-3)
- 4-Acetyl-2,3-difluorophenylboronic acid (CAS 1451390-78-5)
- 3-Acetyl-2,6-difluorophenylboronic acid (CAS 1451390-81-0)
- 2,4-Difluorophenylboronic Acid Pinacol Ester (CAS 288101-48-4)
- 4-Acetyl-2,3-difluorophenylboronic acid pinacol ester (CAS 2121511-81-5)
Recommended Standards
- Gadolinium 158 (CAS 15068-71-0)
- (1-Methyl-4-piperidinyl)magnesium Chloride (0.5M THF)DISCONTINUED (CAS 63463-36-5)
- Manganese(III) oxide (CAS 1317-34-6)
- (2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)boronic acid (CAS 70523-22-7)
- N-Hydroxy-5-methyl-1,2,4-oxadiazole-3-carboximidamide (CAS 162969-65-5)
- 3-Bromo-1-(tetrahydro-2h-pyran-2-yl)-1h-1,2,4-triazole (CAS 1214900-96-5)
- 5-Ethyl-2,3,4,5-tetrahydro-1H-pyrido[2,3-b][1,4]diazepine (CAS 1502129-68-1)
- tert-butyl (4R)-4-azido-3,3-difluoro-piperidine-1-carboxylate (CAS 2460357-28-0)
- Indoramin Hydrochloride (CAS 38821-52-2)
- 1-Deoxy-1-(L-aspartyl)-D-fructose (CAS 31105-02-9)
- N-(2-Amino-5-hydroxy-6-methylpyrimidin-4-yl)-4-hydroxybenzamide (CAS 61581-39-3)
- 3-Chloro-2-methoxypyridine-4-thiol (CAS 2055759-64-1)
- 2,2-Bis(4-methoxyphenyl)acetic acid (CAS 4541-73-5)
- Semaglutide impurity 92 (CAS CATO-C4X-222692)
Why CATO?
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