3-(Pyridin-3-yl)-6-(trifluoromethyl)pyridine-2-thiol CAS 1214325-79-7
| CAS No. | 1214325-79-7 |
| Molecular Formula | C11H7F3N2S |
| Molecular Weight | 256.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(Pyridin-3-yl)-6-(trifluoromethyl)pyridine-2-thiol (CAS 1214325-79-7) is a high-purity analytical reference standard with the molecular formula C11H7F3N2S and a molecular weight of 256.25 g/mol.
The molecular framework of 3-(Pyridin-3-yl)-6-(trifluoromethyl)pyridine-2-thiol (C11H7F3N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 3-(Pyridin-3-yl)-6-(trifluoromethyl)pyridine-2-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7F3N2S |
| Molecular Weight | 256.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Pyridin Standards
- 3-(Pyridin-4-yl)-5-(trifluoromethyl)pyridine-2-thiol (CAS 1214327-01-1)
- 5-(Pyridin-3-yl)-6-(trifluoromethyl)pyridine-2-thiol (CAS 1214339-09-9)
- 3-(Pyridin-3-yl)-5-(trifluoromethyl)pyridine-2-thiol (CAS 1214351-20-8)
- 3-(Pyridin-4-yl)-6-(trifluoromethyl)pyridine-2-thiol (CAS 1214362-98-7)
- 5-(Pyridin-4-yl)-6-(trifluoromethyl)pyridine-2-thiol (CAS 1214392-00-3)
- 2-((Pyridin-3-ylmethyl)carbamoyl)benzoic acid (CAS 100872-69-3)
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Recommended Standards
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- 5-Hydroxy-1-methylpiperidin-2-one (CAS 33342-01-7)
- 5-methoxy-2-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)-4H-pyran-4-one (CAS 54620-67-6)
- 1-((2-Chloro-4-nitrophenyl)amino)-2-methylpropan-2-ol (CAS 854666-45-8)
- 3,5-Bis(benzyloxy)benzoyl Chloride (CAS 28917-44-4)
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- 1-(Tert-butoxycarbonyl)-4-(2-(trifluoromethyl)benzyl)piperidine-4-carboxylic acid (CAS 1185076-12-3)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
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