3-(Pyridin-4-yl)-5-(trifluoromethyl)pyridine-2-thiol CAS 1214327-01-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(Pyridin-4-yl)-5-(trifluoromethyl)pyridine-2-thiol.

3-(Pyridin-4-yl)-5-(trifluoromethyl)pyridine-2-thiol (CAS 1214327-01-1), molecular formula C11H7F3N2S and molecular weight 256.25 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-(Pyridin-4-yl)-5-(trifluoromethyl)pyridine-2-thiol (C11H7F3N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-(Pyridin-4-yl)-5-(trifluoromethyl)pyridine-2-thiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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