1-(2-Chloro-4,5-difluorophenyl)ethanone CAS 121872-94-4
| CAS No. | 121872-94-4 |
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 190.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-Chloro-4,5-difluorophenyl)ethanone (CAS 121872-94-4) is a high-purity analytical reference standard with the molecular formula C8H5ClF2O and a molecular weight of 190.57 g/mol.
1-(2-Chloro-4,5-difluorophenyl)ethanone (C8H5ClF2O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 190.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4'-Chloro-2',6'-difluoroacetophenone (CAS 1017777-45-5)
- 1-(4-Chloro-3,5-difluorophenyl)ethan-1-one (CAS 1256352-85-8)
- 2-(2-Chloro-3,6-difluorophenyl)acetaldehyde (CAS 1256477-62-9)
- 2-(3-Chloro-2,6-difluorophenyl)acetaldehyde (CAS 1256479-70-5)
- 1-(6-Chloro-2,3-difluorophenyl)ethan-1-one (CAS 1373920-86-5)
- 1-(3-Chloro-2,4-difluorophenyl)ethanone (CAS 154258-06-7)
- 5-Chloro-2-(difluoromethyl)benzaldehyde (CAS 1554368-81-8)
- 6-Chloro-2,4-difluoro-3-methylbenzaldehyde (CAS 1706435-05-3)
Recommended Standards
- 121639-61-0 (3,4-Difluorophenyl)acetyl chloride DTXSID60562255 (CAS 121639-61-0)
- Voriconazole Impurity 60 (CAS 116622-90-3)
- 2,4-Difluoro-3-methylbenzoyl chloride (CAS 112857-70-2)
- 3,5-Difluoro-4-methylbenzoyl chloride (CAS 103877-74-3)
- 2-Methyl-6-pyrrolidin-2-yl-pyrimidin-4-ol dihydrochloride (CAS 1229623-53-3)
- 5-Bromoadamantan-2-one (CAS 20098-20-8)
- Cbz-L-Tyrosine benzyl ester triflate (CAS 183070-41-9)
- 2-(((Tetrahydro-2H-pyran-2-yl)methyl)thio)acetic acid (CAS 933699-73-1)
- 4-Chloro-6-fluoro-3-iodo-2H-indazole (CAS 887567-83-1)
- 4-Bromo-1-(oxetan-3-yl)-1H-imidazole (CAS 2137549-94-9)
- Ethyl 2-methylisonicotinate (CAS 25635-17-0)
- Monoisohexyl Phthalate (CAS 848131-14-6)
- 9-([1,1'-Biphenyl]-3-yl)-3-broMo-9H-carbazole (CAS 1428551-28-3)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
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