Indapamide Impurity 9 CAS 1219174-77-2
| CAS No. | 1219174-77-2 |
| Molecular Formula | C16H16ClN3O6S2 |
| Molecular Weight | 445.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Indapamide Impurity 9 (C16H16ClN3O6S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Indapamide Impurity 9 (CAS 1219174-77-2) is a certified pharmaceutical impurity reference standard with the molecular formula C16H16ClN3O6S2 and a molecular weight of 445.90 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Indapamide Impurity 9 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16ClN3O6S2 |
| Molecular Weight | 445.90 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Indapamide Standards
- Indapamide Impurity 45 (CAS CATO-C4X-140045)
- Indapamide Impurity 46 (CAS CATO-C4X-140046)
- Indapamide Impurity 49 (CAS CATO-C4X-140049)
- Indapamide Impurity 35 (CAS CATO-C4X-140035)
- Indapamide Impurity 36 (CAS CATO-C4X-140036)
- Indapamide Impurity 28 (CAS CATO-C4X-140028)
- Indapamide Impurity 27 (CAS CATO-C4X-140027)
- Indapamide Impurity 50 (CAS CATO-C4X-140050)
Recommended Standards
- Darolutamide impurity 6 (CAS CATO-C4X-31066)
- Avanafil Impurity 155 (CAS CATO-C4X-1118155)
- Z-Gly-Gly-Phe-chloromethylketone (CAS 35172-59-9)
- Imatinib Impurity 87 (CAS 571187-02-5)
- Rimegepant Impurity 90 (CAS CATO-C4X-248790)
- Thioctic acid Impurity 96 (CAS CATO-C4X-152696)
- Metaraminol Impurity 49 (CAS CATO-C4X-225249)
- N2,N7-Bis(4-chlorophenyl)-9-oxo-9H-fluorene-2,7-disulfonamide (CAS 303059-41-8)
- 4-Bromo-3-nitropyridin-2(1H)-one (CAS 1804509-38-3)
- (E)-6,7-dihydrobenzo[c][1,2,5]oxadiazol-4(5H)-one oxime (CAS 57153-55-6)
- N,N-Dibenzyl-1-(methylsulfonyl)piperidine-3-carboxamide (CAS 1000949-56-3)
- 2,3-Dihydroxyterephthalaldehyde (CAS 148063-59-6)
- 2-Methoxy-5-(pyrimidin-5-yl)aniline (CAS 1249705-75-6)
- Semaglutide impurity 195 (CAS CATO-C4X-2226195)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com