Imatinib Impurity 87 CAS 571187-02-5
| CAS No. | 571187-02-5 |
| Molecular Formula | C24H20ClN5O2 |
| Molecular Weight | 445.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 445.90 g/mol gives Imatinib Impurity 87 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Imatinib Impurity 87 (CAS 571187-02-5), a pharmacopoeial impurity reference standard (molecular formula C24H20ClN5O2, MW 445.90 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Imatinib Impurity 87 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 445.90 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H20ClN5O2 |
| Molecular Weight | 445.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Imatinib Standards
- Imatinib Impurity 67 (CAS 2031255-25-9)
- Imatinib Impurity 70 (CAS CATO-C4X-106870)
- Imatinib Impurity 2 (CAS 796738-74-4)
- Imatinib Impurity 24 (CAS 404844-11-7)
- Imatinib Impurity 65 (CAS CATO-C4X-106865)
- Imatinib Impurity 73 (CAS CATO-C4X-106873)
- Imatinib EP Impurity C (CAS 404844-02-6)
- Imatinib EP Impurity C-d8 (N-Desmethyl Imatinib-d8) (CAS 1185103-28-9)
Recommended Standards
- Neratinib Impurity N1 (CAS 848139-78-6)
- Avanafil Impurity 155 (CAS CATO-C4X-1118155)
- 9,9'-(6-Chloro-1,3,5-triazine-2,4-diyl)bis(9H-carbazole) (CAS 877615-05-9)
- Indapamide Impurity 45 (CAS CATO-C4X-140045)
- Posaconazole Impurity 87 (CAS 1230634-17-9)
- Cinacalcet Impurity 90 (CAS CATO-C4X-105990)
- Cefmetazole Impurity 16 (CAS CATO-C4X-150716)
- (E)-3-(5-Methylisoxazol-3-yl)acrylic acid (CAS 1065478-29-6)
- Methyl 2-((2-chloro-5-nitropyrimidin-4-yl)amino)benzoate (CAS 66427-76-7)
- 6-(4-Fluorophenyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 477320-29-9)
- N-(2-Methoxyethyl)-N-(4-methyloxazol-2-yl)butyramide (CAS 62124-35-0)
- 474943-83-4 Dimethyl Sphingosine-1-Phosphate (d18:1) (CAS 474943-83-4)
- 5-(Benzo[d]isoxazol-3-ylmethyl)-4-(p-tolyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 861206-87-3)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com