Gemcitabine Impurity 26 CAS 122111-12-0
| CAS No. | 122111-12-0 |
| Molecular Formula | C5H6F2O4 |
| Molecular Weight | 168.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Gemcitabine Impurity 26.
CATO supplies Gemcitabine Impurity 26 (CAS 122111-12-0), a pharmacopoeial impurity reference standard (molecular formula C5H6F2O4, MW 168.10 g/mol) used for the identification and quantification of trace impurities in APIs.
Gemcitabine Impurity 26 (C5H6F2O4) contains a carbohydrate-derived structure, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Gemcitabine Impurity 26 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6F2O4 |
| Molecular Weight | 168.10 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Gemcitabine Standards
- Gemcitabine Impurity 22 (CAS 95058-77-8)
- Gemcitabine Impurity 25 (CAS 166275-25-8)
- Gemcitabine Impurity 19 (CAS 15186-48-8)
- Gemcitabine Impurity N2 (CAS 928797-50-6)
- Gemcitabine Impurity 17 (CAS 95058-92-7)
- Gemcitabine Impurity 36 (CAS 166376-97-2)
- Gemcitabine Impurity 23 (CAS 82188-74-7)
- Gemcitabine Impurity N1 (CAS 103882-85-5)
Recommended Standards
- 4-nitronicotinic acid (CAS 100367-58-6)
- (Z)-1,1,1-trifluoro-4-methoxypent-3-en-2-one (CAS 102145-82-4)
- Dimethyl difluoromalonate (CAS 379-95-3)
- 1-(2,2,2-Trifluoroethyl)cyclopropane-1-carboxylic acid (CAS 1026283-70-4)
- Abiraterone Impurity N8 (CAS 2487-48-1)
- Ledipasvir Impurity 2 (CAS CATO-C4X-33132)
- Abiraterone Impurity 60 (CAS 1868064-51-0)
- 4,5-Dichloro-6-ethyl-2-methylpyrimidine (CAS 141602-39-3)
- 2-(1-methylcyclopentyl)ethan-1-amine (CAS 933695-49-9)
- Diethyl 2-((5-(p-tolyl)furan-2-yl)methylene)malonate (CAS 304896-38-6)
- Epoxybergamottin (CAS 206978-14-5)
- 2-Amino-N-(3,4-dimethoxyphenethyl)thiophene-3-carboxamide (CAS 590360-06-8)
- Atrasentan Impurity 10 (CAS 195707-70-1)
- Allo-D-Ile12-Tirzepatide (CAS CATO-CPTD788963)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com