Gemcitabine Impurity 22 CAS 95058-77-8

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.95058-77-8
Molecular FormulaC5H6F2O4
Molecular Weight168.10 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Gemcitabine Impurity 22 CAS 95058-77-8 chemical structure

Description

The molecular framework of Gemcitabine Impurity 22 (C5H6F2O4) is characterized by a carbohydrate-derived structure, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Gemcitabine Impurity 22 (CAS 95058-77-8) is a certified pharmaceutical impurity reference standard with the molecular formula C5H6F2O4 and a molecular weight of 168.10 g/mol.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Gemcitabine Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC5H6F2O4
Molecular Weight168.10 g/mol
Purity>90%
StorageStore at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityHygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1984
Halogen ContentF-containing

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