5-Chloro-3-{[3-(trifluoromethyl)phenyl]methyl}-1,2,4-thiadiazole CAS 1221346-00-4
| CAS No. | 1221346-00-4 |
| Molecular Formula | C10H6ClF3N2S |
| Molecular Weight | 278.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-3-{[3-(trifluoromethyl)phenyl]methyl}-1,2,4-thiadiazole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chloro-3-{[3-(trifluoromethyl)phenyl]methyl}-1,2,4-thiadiazole (CAS 1221346-00-4), a certified reference material (molecular formula C10H6ClF3N2S, MW 278.68 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H6ClF3N2S, 5-Chloro-3-{[3-(trifluoromethyl)phenyl]methyl}-1,2,4-thiadiazole contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 278.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6ClF3N2S |
| Molecular Weight | 278.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 7-(Chlorosulfonyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid (CAS 66410-36-4)
- 3,4-Di-O-benzyl DL-threo-Droxidopa Hydrochloride (CAS 73594-43-1)
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- 2-((6-Bromo-3-ethyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)acetamide (CAS 786726-44-1)
- 2-Propenoic acid, 2-methyl-, polymer with butyl 2-propenoate, 2-oxiranylmethyl 2-methyl-2-propenoate and 2-propenenitrile (CAS 26355-73-7)
- Tert-butyl 4-([1,2,4]triazolo[1,5-a]pyrazin-5-yl)piperazine-1-carboxylate (CAS 1803585-53-6)
- 2-Bromo-4,6-diisopropylpyrimidin-5-amine (CAS 2387294-66-6)
- (Chloromethyl)cyclohexane(mix) (CAS 26895-68-1)
- (R)-2-amino-4-(3-bromophenyl)butanoic acid (CAS 1260596-20-0)
- 3-Fluorodibenz[b,e]oxepin-11(6H)-one (CAS 114312-48-0)
- Myelin Basic Protein (85-99) Peptide Antagonist (CAS 444305-16-2)
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