4-(1,3-dihydro-2-benzofuran-5-yl)-1,3-thiazol-2-amine CAS 1221722-43-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(1,3-dihydro-2-benzofuran-5-yl)-1,3-thiazol-2-amine.

4-(1,3-dihydro-2-benzofuran-5-yl)-1,3-thiazol-2-amine (CAS 1221722-43-5), molecular formula C11H10N2OS and molecular weight 218.27 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-(1,3-dihydro-2-benzofuran-5-yl)-1,3-thiazol-2-amine (C11H10N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(1,3-dihydro-2-benzofuran-5-yl)-1,3-thiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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