2-((2-(Azepan-1-yl)-6-methylpyrimidin-4-yl)oxy)-N-(2-chloro-4-fluorophenyl)acetamide CAS 1226434-87-2
| CAS No. | 1226434-87-2 |
| Molecular Formula | C19H22ClFN4O2 |
| Molecular Weight | 392.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-((2-(Azepan-1-yl)-6-methylpyrimidin-4-yl)oxy)-N-(2-chloro-4-fluorophenyl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-((2-(Azepan-1-yl)-6-methylpyrimidin-4-yl)oxy)-N-(2-chloro-4-fluorophenyl)acetamide (CAS 1226434-87-2) is a high-purity analytical reference standard with the molecular formula C19H22ClFN4O2 and a molecular weight of 392.85 g/mol.
The molecular framework of 2-((2-(Azepan-1-yl)-6-methylpyrimidin-4-yl)oxy)-N-(2-chloro-4-fluorophenyl)acetamide (C19H22ClFN4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C19H22ClFN4O2 |
| Molecular Weight | 392.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
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- 2-(6-(Azepan-1-yl)-2-(3-(trifluoromethyl)phenyl)pyrimidin-4-yl)-N-hydroxyacetamide (CAS 42055-79-8)
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Recommended Standards
- H-Glu-Gly-Arg-chloromethylketone (CAS 65113-67-9)
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- Avanafil Impurity 40 (CAS 1638497-25-2)
- 1-[(4-Chlorophenyl)methyl]-3-{2-[(4-fluorophenyl)methoxy]phenyl}-1H-pyrazole (CAS 477713-50-1)
- 1-(6-Amino-4,4-dimethyl-3,4-dihydroquinolin-1(2H)-yl)-2,2,2-trifluoroethanone (CAS 1627696-33-6)
- Iridium ((2,2-Bipyridine-N,N)bis[2-(2-pyridinyl)phenyl-C,N] Hexaflouorophosphate (CAS 106294-60-4)
- 1-Iodo-4-(2,2,2-trifluoroethoxy)benzene (CAS 530080-17-2)
- (αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxy-4-(phenylmethoxy)-benzenepropanoic Acid Ethyl Ester (CAS 382596-26-1)
- Trelagliptin-13C-d3 (CAS 2707203-34-5)
- 3-(5-Methylisoxazol-3-yl)propanoic acid (CAS 80073-32-1)
- (Z)-3-(((4-chlorobenzyl)oxy)imino)-1-phenylindolin-2-one (CAS 341964-28-1)
- 6-Bromo-5-(trifluoromethyl)-1H-indazole (CAS 1396762-44-9)
- Opicapone Impurity 83 (CAS 1428009-74-8)
- HA Peptide (CAS 92000-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com