Pazopanib Impurity 37 CAS 1226500-02-2
| CAS No. | 1226500-02-2 |
| Molecular Formula | C26H23ClN10 |
| Molecular Weight | 510.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Pazopanib Impurity 37 (CAS 1226500-02-2), a pharmacopoeial impurity reference standard (molecular formula C26H23ClN10, MW 510.98 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Pazopanib Impurity 37 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 510.98 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Pazopanib Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H23ClN10 |
| Molecular Weight | 510.98 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 10 |
Related Pazopanib Standards
- Pazopanib Impurity 39 (CAS 1252927-44-8)
- Pazopanib Impurity 50 (CAS 1226500-00-0)
- Pazopanib Impurity 52 (CAS CATO-C4X-172552)
- Pazopanib Impurity 44(Mixture of Isomers) (CAS CATO-C4X-172544)
- Pazopanib impurity 48 (CAS CATO-C4X-172548)
- Pazopanib Impurity N7 (CAS 1414375-50-0)
- Pazopanib Impurity 2 (CAS 1821666-73-2)
- Pazopanib Impurity 54 (CAS CATO-C4X-172554)
Recommended Standards
- ((Oxoboryl)oxy)(4-((5-((3-(trifluoromethyl)phenyl)carbamoyl)quinolin-2-yl)oxy)pyrimidin-2-yl)boramidic acid (CAS 2304634-07-7)
- Eldecalcitol Impurity 37 (CAS 235107-98-9)
- Apixaban Impurity 60 (CAS CATO-C4X-108860)
- Fluocinolone Acetonide Impurity 15 (CAS 1181-32-4)
- Digoxin EP Impurity E (CAS 52589-12-5)
- Pentoxifylline impurity 36 (CAS CATO-C4X-172836)
- Meclofenoxate Impurity 2 (CAS 4841-22-9)
- (E)-N-(3-([3,3'-Bithiophen]-5-ylmethoxy)benzyl)-N-ethyl-6,6-dimethylhept-2-en-4-yn-1-amine hydrochloride (CAS 136719-25-0)
- 2-Phenylethynamine (CAS 85739-51-1)
- [2-(1-naphthylmethyl)-1H-benzimidazol-1-yl]acetic acid (CAS 919939-22-3)
- Sulindac Impurity 9 (CAS CATO-C4X-29309)
- 2-((5-Thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)thio)acetonitrile (CAS 62770-09-6)
- Anantin (linear sequence) trifluoroacetate salt (CAS 348600-37-3)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com