Pazopanib Impurity 39 CAS 1252927-44-8
| CAS No. | 1252927-44-8 |
| Molecular Formula | C27H25ClN10 |
| Molecular Weight | 525.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Pazopanib Impurity 39 (C27H25ClN10) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 20.0, corresponding to approximately 20 ring(s) or double-bond equivalent(s). With a molecular weight of 525.01 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Pazopanib Impurity 39 (CAS 1252927-44-8) is a certified pharmaceutical impurity reference standard with the molecular formula C27H25ClN10 and a molecular weight of 525.01 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Pazopanib Impurity 39 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H25ClN10 |
| Molecular Weight | 525.01 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 10 |
Related Pazopanib Standards
- Pazopanib Impurity 37 (CAS 1226500-02-2)
- Pazopanib Impurity 50 (CAS 1226500-00-0)
- Pazopanib Impurity 52 (CAS CATO-C4X-172552)
- Pazopanib Impurity 44(Mixture of Isomers) (CAS CATO-C4X-172544)
- Pazopanib impurity 48 (CAS CATO-C4X-172548)
- Pazopanib Impurity N7 (CAS 1414375-50-0)
- Pazopanib Impurity 2 (CAS 1821666-73-2)
- Pazopanib Impurity 54 (CAS CATO-C4X-172554)
Recommended Standards
- (4-(4-Chlorophenyl)-5-(2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl)-1H-pyrazol-1-yl)(3-methoxyphenyl)methanone (CAS 477762-84-8)
- 2-Chloro-3,4-bis((4-methoxybenzyl)oxy)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide (CAS 1225208-44-5)
- Apixaban Impurity 10 (CAS 1421823-20-2)
- 2-(Benzylsulfanyl)-5-(4-chlorophenyl)-4-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}pyrimidine (CAS 478248-93-0)
- Tolvaptan Impurity 60 (CAS CATO-C4X-195560)
- Perampanel Impurity 39 (CAS CATO-C4X-243039)
- Lansoprazole Impurity 49 HCl (CAS 4370-22-3)
- 6-CHLOROFLAVONE (CAS 10420-73-2)
- 2,4-Dichloro-5-(n-(6-ethoxybenzo[d]thiazol-2-yl)sulfamoyl)benzoic acid (CAS 692745-62-3)
- (4R)-azepan-4-ol;hydrochloride (CAS 2365390-45-8)
- 5-(4-Triflluoromethylphenyl)-1,3,4-thiadiazole-2-carboxylic acid (CAS 1388071-34-8)
- 1-(4-(Phenylthio)phenyl)-2-(pyrrolidin-1-ylimino)ethanone (CAS 25555-26-4)
- 4-Propyltetrahydro-2H-pyran-4-ol (CAS 1340577-31-2)
- Semaglutide Impurity 133 (CAS CATO-C4X-2226133)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com