2-Amino-3-iodo-6-(trifluoromethyl)pyridine CAS 1227602-97-2
| CAS No. | 1227602-97-2 |
| Molecular Formula | C6H4F3IN2 |
| Molecular Weight | 288.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Amino-3-iodo-6-(trifluoromethyl)pyridine (CAS 1227602-97-2), molecular formula C6H4F3IN2 and molecular weight 288.01 g/mol, is a CATO reference standard with documented purity and traceability.
2-Amino-3-iodo-6-(trifluoromethyl)pyridine (C6H4F3IN2) contains a nitrile group, fluorine/iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H4F3IN2 |
| Molecular Weight | 288.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 3-Amino-4-iodo-2-(trifluoromethyl)pyridine (CAS 1227509-56-9)
- 2-Amino-4-iodo-5-(trifluoromethyl)pyridine (CAS 1227515-42-5)
- 2-Amino-3-iodo-4-(trifluoromethyl)pyridine (CAS 1227602-87-0)
- 2-Amino-3-iodo-5-(trifluoromethyl)pyridine (CAS 211308-82-6)
- 2-Amino-6-iodopyrido[2,3-d]pyrimidin-4(1H)-one (CAS 91997-12-5)
- 2-Amino-3-trifluoromethylpyridine-5-boronic acid pinacol ester, 97% (CAS 947249-01-6)
- 2-Amino-4-trifluoromethylpyridine-5-boronic acid pinacol ester, 97% (CAS 944401-57-4)
- 2-Amino-6-bromo-4-((trifluoromethyl)thio)phenol (CAS 1432075-81-4)
Recommended Standards
- 5-Iodo-2-(trifluoromethyl)pyridin-4-amine (CAS 1239462-10-2)
- 5-Iodo-6-(trifluoromethyl)pyridin-2-amine (CAS 1227596-12-4)
- 5-Iodo-2-(trifluoromethyl)phenol (CAS 1243312-81-3)
- 4-Iodo-6-(trifluoromethyl)pyridin-2-amine (CAS 1227581-86-3)
- Methyl (1-hydroxy-2-methylpropan-2-yl)phenylalaninate (CAS 1431859-26-5)
- 2-methyl-1-(1-methylpiperidin-4-yl)piperazine (CAS 1267350-91-3)
- (5E)-5-[(2-Chloropyridin-3-yl)methylene]-2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one 1142201-58-8 (CAS 1142201-58-8)
- Sulfasalazine EP Impurity E Trisodium Salt (CAS 1391062-34-2 (free acid))
- 5-(Thiophen-3-yl)-3-(trifluoromethyl)-1H-pyrazole (CAS 2408886-65-5)
- 4-Fluoro-3-methyl-1H-indole-2-carboxylic acid (CAS 1417357-90-4)
- N-Cyclopropyl-3-(1H-indazol-5-yl)-4-methylbenzamide (CAS 651780-47-1)
- 2-Chloro-6-fluorobenzyl 1-(2-chloro-6-fluorobenzyl)azetidine-3-carboxylate (CAS 1289385-42-7)
- Cyclopropanesulfinic acid (CAS 761365-62-2)
- Experimental Allergic Encephalitogenic Peptide (CAS 29705-92-8)
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