Flurbiprofen Impurity 86 CAS 1233402-20-4
| CAS No. | 1233402-20-4 |
| Molecular Formula | C12H8BrF |
| Molecular Weight | 251.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 251.09 g/mol gives Flurbiprofen Impurity 86 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Flurbiprofen Impurity 86 (CAS 1233402-20-4, C12H8BrF) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Flurbiprofen Impurity 86 (C12H8BrF) contains fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Flurbiprofen Impurity 86 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8BrF |
| Molecular Weight | 251.09 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
Related Flurbiprofen Standards
- Flurbiprofen Impurity 27 (CAS 136649-30-4)
- Flurbiprofen Impurity 154 (CAS 1515573-52-0)
- Flurbiprofen Impurity 39 (CAS 53591-98-3)
- Flurbiprofen Impurity 73 (CAS CATO-C4X-144473)
- Flurbiprofen-d3 (CAS 1185133-81-6)
- (R)-Flurbiprofen D3 (CAS CATO-C4X-1444136)
- (S)-Flurbiprofen D3 (CAS CATO-C4X-1444137)
- Flurbiprofen impurity 123 (CAS CATO-C4X-1444123)
Recommended Standards
- 5-Amino-2-bromobenzenesulfonamide (CAS 100367-51-9)
- 3-Amino-4-bromobenzenesulfonamide (CAS 100367-90-6)
- 4-Bromo-2-fluorobiphenyl (CAS 41604-19-7)
- 2-{[(4-bromo-1h-pyrazol-1-yl)methyl]sulfanyl}acetic acid (CAS 1006319-28-3)
- Carfilzomib Impurity 65 (CAS CATO-C4X-102265)
- Urapidil Impurity 57 (CAS CATO-C4X-192457)
- Ceftriaxone EP Impurity E (CAS CATO-C4X-11637)
- cis-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol (CAS 138090-06-9)
- 2-Chloro-1-(4-phenylpiperazin-1-yl)propan-1-one hydrochloride (CAS 1049747-22-9)
- N-(2-Nitro-4-propylphenyl)acetamide (CAS 99841-36-8)
- 4-(2-Methoxybenzyl)piperidin-4-ol Hydrochloride (CAS 1803592-30-4)
- 3,4,5-Trimethoxybenzimidamide (CAS 4156-70-1)
- 2-(5-Isopropyl-4h-1,2,4-triazol-3-yl)ethanethioamide (CAS 1305712-90-6)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
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