Carfilzomib Impurity 65 CAS CATO-C4X-102265
| CAS No. | CATO-C4X-102265 |
| Molecular Formula | C40H59N5O8 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Carfilzomib Impurity 65 (CAS CATO-C4X-102265), a pharmacopoeial impurity reference standard (molecular formula C40H59N5O8C2HF3O2, MW 851.96 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Carfilzomib Impurity 65 (C40H59N5O8C2HF3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 851.96 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C40H59N5O8 2*C2HF3O2 |
| Molecular Weight | 851.96 g/mol |
| Purity | >85% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Carfilzomib Standards
- CarfilzomiB impurity 12 (CAS 100564-78-1)
- Carfilzomib Impurity 36 (CAS 1140908-89-9)
- Carfilzomib Impurity 50 (CAS 129603-01-6)
- Carfilzomib Impurity N2 (CAS 1396006-45-3)
- Carfilzomib Impurity N1 (CAS 1396006-47-5)
- Carfilzomib Impurity 28 (CAS 143415-51-4)
- Carfilzomib Impurity 25 (CAS 15136-32-0)
- Carfilzomib Impurity 71 (CAS 1528769-14-3)
Recommended Standards
- Roxadustat Impurity 172 (CAS CATO-C4X-2213172)
- Iopamidol EP Impurity A (CAS 60166-98-5)
- Apremilast Impurity 26 (CAS CATO-C4X-100926)
- 2-Chloro-N-(3-cyano-benzyl)-N-isopropyl-acetamide (CAS 1353963-23-1)
- 2-(Aminomethyl)-3-bromo-4-(difluoromethyl)-5-iodopyridine (CAS 1804668-99-2)
- Ozagrel Sodium (CAS 189224-26-8)
- 106366-23-8 2-(2-Phenethyl)-1-pyrroline 2-(2-Phenylethyl)-1-pyrroline 3,4-Dihydro-5-(2-phenylethyl)-2H-pyrrole (CAS 106366-23-8)
- 1-(5-(Dimethylamino)pyrazin-2-yl)ethanone (CAS 214701-22-1)
- 4-Bromo-6-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-5-carbaldehyde (CAS 2852768-02-4)
- Tau Peptide (294-305) (human) trifluoroacetate salt (CAS 1428135-29-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com