Flunarizine Impurity N1 HCl CAS 123375-94-0(free base)
| CAS No. | 123375-94-0(free base) |
| Molecular Formula | C26H26F2N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Flunarizine Impurity N1 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Flunarizine Impurity N1 HCl (CAS 123375-94-0(free base), C26H26F2N2OHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Flunarizine Impurity N1 HCl (C26H26F2N2OHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 456.96 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C26H26F2N2O HCl |
| Molecular Weight | 456.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Flunarizine Standards
- Flunarizine impurity 43 (CAS 1133842-25-7)
- Flunarizine Impurity 59 (CAS 114312-65-1)
- Flunarizine impurity 57 (CAS 114374-24-2)
- Flunarizine Impurity N1 (CAS 123375-94-0)
- Flunarizine impurity 46 (CAS 1368426-98-5(free base))
- Flunarizine Impurity 32 (CAS 141528-78-1)
- Flunarizine Impurity 26 (CAS 144917-53-3)
- Flunarizine impurity 47 (CAS 148728-47-6)
Recommended Standards
- Tadalafil Impurity 113 (CAS 68807-89-6)
- FCN437 Impurity 3 (CAS CATO-C4X-33243)
- Nabumetone Impurity 10 (CAS CATO-C4X-284810)
- Oxybutynin Impurity 3 (CAS 1215677-72-7)
- 2-Bromo-1-(5-chloro-2-thienyl)ethanone (CAS 57731-17-6)
- Salicylic Acid Impurity 20 (CAS CATO-C4X-190220)
- 4-[2-(Dimethylamino)ethoxy]benzonitrile (CAS 24197-95-3)
- 2,2,2-Trichloro-N-pentylacetimidamide (CAS 35518-70-8)
- 2-Bromo-1-fluoro-3-methyl-5-nitrobenzene (CAS 1426805-92-6)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
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