Rupatadine Impurity 4 CAS 1235342-53-6
| CAS No. | 1235342-53-6 |
| Molecular Formula | C7H8BrN |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rupatadine Impurity 4 is closely related to a nitrile group, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Rupatadine Impurity 4 (CAS 1235342-53-6, C7H8BrNHBr) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Rupatadine Impurity 4 (C7H8BrNHBr) contains a nitrile group, bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rupatadine Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8BrN HBr |
| Molecular Weight | 266.96 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Rupatadine Standards
- Rupatadine Impurity 21 (CAS 1007089-84-0)
- Rupatadine Impurity 24 (CAS 100910-66-5)
- Rupatadine Impurity 3 (CAS 102074-19-1)
- Rupatadine impurity 1 (CAS 1118754-56-5)
- Rupatadine impurity 14 (CAS 1210824-61-5)
- Rupatadine EP Impurity C (CAS 1224515-72-3)
- Rupatadine EP Impurity A (CAS 1354055-68-7)
- Rupatadine Impurity 20 (CAS 1422960-88-0)
Recommended Standards
- Empagliflozin Impurity 126 (CAS CATO-C4X-1065126)
- Solifenacin Succinate EP Impurity F (CAS 774517-20-3)
- Bilastine Impurity 41 (CAS 2761944-43-6)
- 2-(Aminomethyl)-6-(difluoromethyl)-4-iodo-3-methylpyridine (CAS 1805547-16-3)
- 6-Chloro-2-ethylpyrimidin-4-amine (CAS 98134-36-2)
- 2-Ethyl-N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)butanamide (CAS 893970-24-6)
- Ethyl 7-(4-hexyloxyphenyl)-7-oxoheptanoate (CAS 898757-93-2)
- Methyl 1-amino-7-(3-fluorophenyl)isoquinoline-4-carboxylate (CAS 1449278-33-4)
- N-(2-amino-1-phenylethyl)-3-methoxyaniline (CAS 1267895-82-8)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com