Abiraterone Impurity 76 CAS 1236-14-2
| CAS No. | 1236-14-2 |
| Molecular Formula | C21H30O2 |
| Molecular Weight | 314.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Abiraterone Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Abiraterone Impurity 76 (CAS 1236-14-2) is a certified pharmaceutical impurity reference standard with the molecular formula C21H30O2 and a molecular weight of 314.46 g/mol.
The molecular framework of Abiraterone Impurity 76 (C21H30O2) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H30O2 |
| Molecular Weight | 314.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Abiraterone Standards
- Abiraterone Impurity N8 (CAS 2487-48-1)
- Abiraterone Impurity 74 (CAS 38391-29-6)
- Abiraterone Impurity 9 (CAS 566-19-8)
- Abiraterone Impurity 81 (CAS 2118-31-2)
- Abiraterone Impurity 47 (CAS CATO-C4X-107047)
- Abiraterone Impurity 49 (CAS CATO-C4X-107049)
- Abiraterone Impurity N6 (CAS 853-23-6)
- Abiraterone Impurity 13 (CAS 154229-20-6)
Recommended Standards
- 3,6,9,12,15-Pentaoxaheptadecane-1,17-dithiol 89141-22-0 Hexa(ethylene glycol) dithiol Tetraethylene glycol di(ethanediol) (CAS 89141-22-0)
- Rocuronium Impurity 12 (CAS 50588-42-6)
- 17.alpha.-Pregn-5-en-20-yne-3.beta.,17.beta.-diol 3604-60-2 Androst-5-ene-3.beta., 17-ethynyl- NSC-17098 NSC17098 Pregn-5-en-20-yne-3, (3.beta.,17.alpha.)- (CAS 3604-60-2)
- Rocuronium Impurity 51 (CAS 103088-58-0)
- Nizatidine EP Impurity E (CAS 188666-11-7)
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- Ruxolitinib Impurity 123 (CAS CATO-C4X-2058123)
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- 4-(5-(2-Ethoxyphenyl)-1,2,4-oxadiazol-3-yl)-1-phenylpyrrolidin-2-one (CAS 1171846-72-2)
- Gastric Inhibitory Polypeptide (6-30) amide (human) (CAS 1139691-72-7)
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