Abiraterone Impurity N6 CAS 853-23-6
| CAS No. | 853-23-6 |
| Molecular Formula | C21H30O3 |
| Molecular Weight | 330.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Abiraterone Impurity N6.
Abiraterone Impurity N6 (CAS 853-23-6) is a certified pharmaceutical impurity reference standard with the molecular formula C21H30O3 and a molecular weight of 330.46 g/mol.
Owing to a steroid core, a hydroxyl group, an ether linkage, Abiraterone Impurity N6 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 330.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Abiraterone Impurity N6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H30O3 |
| Molecular Weight | 330.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Abiraterone Standards
- Abiraterone Impurity 13 (CAS 154229-20-6)
- Abiraterone Impurity 47 (CAS CATO-C4X-107047)
- Abiraterone Impurity 49 (CAS CATO-C4X-107049)
- Abiraterone Impurity N1 (CAS 2118-32-3)
- Abiraterone Impurity 76 (CAS 1236-14-2)
- Abiraterone Impurity 27 (CAS 154229-21-7)
- Abiraterone (CAS 154229-19-3)
- Abiraterone Related Compound 9 (CAS 154229-26-2)
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- Hordatine B (CAS 10502-21-3)
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