Bortezomib Impurity 33 CAS 73058-37-4
| CAS No. | 73058-37-4 |
| Molecular Formula | C15H15N3O3 |
| Molecular Weight | 285.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Bortezomib Impurity 33 (CAS 73058-37-4, C15H15N3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Bortezomib Impurity 33 (C15H15N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Bortezomib Impurity 33 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H15N3O3 |
| Molecular Weight | 285.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 3 |
Related Bortezomib Standards
- Bortezomib Impurity 40 (CAS 87304-47-0)
- Bortezomib Impurity N46 (CAS 85167-14-2)
- Bortezomib Impurity 49 (CAS 948294-96-0)
- Bortezomib Impurity 67 (CAS 2308-61-4)
- Bortezomib Impurity 16 (CAS CATO-C4X-107216)
- Bortezomib Impurity 29 (CAS CATO-C4X-107229)
- Bortezomib Impurity 2 (CAS 114457-94-2)
- Bortezomib Impurity 31 (CAS 1608986-16-8)
Recommended Standards
- Topiroxostat Impurity 55 (CAS CATO-C4X-105555)
- Alogliptin Impurity 50 (CAS 1883825-48-6)
- Verazide (CAS 93-47-0)
- Benserazide impurity 45 (CAS CATO-C4X-142745)
- Fluvoxamine Impurity 54 (CAS CATO-C4X-195154)
- Olmesartan Impurity 94 (CAS CATO-C4X-109794)
- Amorolfine EP Impurity A(Mixture of Enantiomers) (CAS CATO-C4X-15424)
- n-Cyclobutyl-4-fluoro-2-methylaniline (CAS 1248065-83-9)
- Landiolol Impurity 30 (CAS CATO-C4X-262130)
- 2,6-Diethynylisonicotinic acid (CAS 2363048-11-5)
- 4-Fluoro-N-methyl-3-nitroaniline (CAS 24773-12-4)
- 2,3-Dichloropropionitrile (CAS 2601-89-0)
- 6-Fluoro-2-methylbenzoxazole (CAS 312600-96-7)
- Des-Ser32-Tirzepatide (CAS CATO-CPTD788942)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com