Edaravone Impurity 6 CAS 124009-63-8
| CAS No. | 124009-63-8 |
| Molecular Formula | C30H26N6O3 |
| Molecular Weight | 518.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 518.57 g/mol gives Edaravone Impurity 6 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Edaravone Impurity 6 (CAS 124009-63-8, C30H26N6O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Edaravone Impurity 6 (C30H26N6O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Edaravone Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H26N6O3 |
| Molecular Weight | 518.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 6 |
Related Edaravone Standards
- Edaravone Impurity 4 (CAS 68195-63-1)
- Edaravone impurity 41 (CAS CATO-C4X-106241)
- Edaravone impurity 37 (CAS CATO-C4X-106237)
- Edaravone impurity 42 (CAS 153952-07-9)
- Edaravone impurity 53 (CAS 92558-29-7)
- Edaravone Impurity 58 (CAS CATO-C4X-106258)
- Edaravone impurity 55 (CAS CATO-C4X-106255)
- Edaravone Impurity 59 (CAS CATO-C4X-106259)
Recommended Standards
- Triamcinolone Acetonide Impurity 51 (CAS 2796-78-3)
- CPI-1205 (CAS 1621862-70-1)
- (2E)-3-[4-(Benzyloxy)phenyl]-1-{3-[1-({2-fluoro-[1,1'-biphenyl]-4-yl}oxy)ethyl]-1H-pyrazol-1-yl}prop-2-en-1-one (CAS 477710-95-5)
- Fmoc-Ala-(Dmb)Gly-OH (CAS 1188402-17-6)
- Flurbiprofen Impurity 37 (CAS 56430-67-2)
- Cefoperazone Impurity 13 (CAS CATO-C4X-114913)
- Ranolazine Impurity 12 (CAS 755711-09-2)
- (S)-5-Oxopiperazine-2-carboxylic acid hydrochloride (CAS 1621961-57-6)
- 3-cyclohexanecarbonyl-4H-1,2,4-triazole (CAS 1486831-40-6)
- 3-Bromo-5-methyl-2-(4H-1,2,4-triazol-4-yl)pyridine (CAS 1123169-57-2)
- (S)-1-(3-bromo-5-(trifluoromethyl)phenyl)but-3-en-1-amine (CAS 1269820-65-6)
- L-Glutamic γ-monohydroxamate (CAS 1955-67-5)
- 3-(Cyclopropylamino)-4-(N,N-dimethylamino)-tetrahydrofuran (CAS 728008-15-9)
- Neuropeptide K, porcine (CAS 106441-70-7)
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