1-[3,5-Bis(trifluoromethyl)benzoyl]-3-methylpiperazine CAS 1240567-35-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1240567-35-4
Molecular FormulaC14H14F6N2O
Molecular Weight340.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-[3,5-Bis(trifluoromethyl)benzoyl]-3-methylpiperazine CAS 1240567-35-4 chemical structure

Description

The occurrence of 1-[3,5-Bis(trifluoromethyl)benzoyl]-3-methylpiperazine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 1-[3,5-Bis(trifluoromethyl)benzoyl]-3-methylpiperazine (CAS 1240567-35-4), a certified reference material (molecular formula C14H14F6N2O, MW 340.26 g/mol) for analytical method development and quality control.

The molecular framework of 1-[3,5-Bis(trifluoromethyl)benzoyl]-3-methylpiperazine (C14H14F6N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-[3,5-Bis(trifluoromethyl)benzoyl]-3-methylpiperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H14F6N2O
Molecular Weight340.26 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2

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