Metoclopramide Impurity 83 CAS 1242047-99-9
| CAS No. | 1242047-99-9 |
| Molecular Formula | C28H43ClN6O4 |
| Molecular Weight | 563.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metoclopramide Impurity 83.
CATO supplies Metoclopramide Impurity 83 (CAS 1242047-99-9), a pharmacopoeial impurity reference standard (molecular formula C28H43ClN6O4, MW 563.13 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Metoclopramide Impurity 83 (C28H43ClN6O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H43ClN6O4 |
| Molecular Weight | 563.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Metoclopramide Standards
- Metoclopramide Impurity 109 (CAS CATO-C4X-1415109)
- Metoclopramide impurity 54 (CAS CATO-C4X-141554)
- Metoclopramide impurity 56 (CAS 1242048-03-8)
- Metoclopramide impurity 60 (CAS 1242047-97-7)
- Metoclopramide Impurity 124 (CAS CATO-C4X-1415124)
- Metoclopramide Impurity 123 (CAS CATO-C4X-1415123)
- Metoclopramide impurity 52 (CAS CATO-C4X-141552)
- Metoclopramide Impurity 110 (CAS CATO-C4X-1415110)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com